AutismKB 2.0

Annotation Details for MAPK8IP2


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Basic Information Top
Gene Symbol:MAPK8IP2 ( IB2,JIP2,PRKM8IPL )
Gene Full Name: mitogen-activated protein kinase 8 interacting protein 2
Band: 22q13.33
Quick LinksEntrez ID:23542; OMIM: 607755; Uniprot ID:JIP2_HUMAN; ENSEMBL ID: ENSG00000008735; HGNC ID: 6883
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10490659
GO:0014069ISS-postsynaptic density-
GO:0043025IEA-neuronal cell body-
GO:0043234IEA-protein complex-
GO ID Evidence Qualifier GO_term References
GO:0001540NAS-amyloid-beta binding12023290
GO:0005078NAS-MAP-kinase scaffold activity10490659
GO:0005198TAS-structural molecule activity10490659
GO:0005515IPI-protein binding16273093
GO:0019894ISS-kinesin binding-
GO:0019901IPI-protein kinase binding10490659
GO:0032403IEA-protein complex binding-
GO ID Evidence Qualifier GO_term References
GO:0001662ISS-behavioral fear response-
GO:0007172TAS-signal complex assembly10490659
GO:0007254IEA-JNK cascade-
GO:0007617IEA-mating behavior-
GO:0010469ISS-regulation of receptor activity-
GO:0032874IEA-positive regulation of stress-activated MAPK cascade-
GO:0035176ISS-social behavior-
GO:0046328IDA-regulation of JNK cascade10490659
GO:0046958ISS-nonassociative learning-
GO:0048813ISS-dendrite morphogenesis-
GO:0051966ISS-regulation of synaptic transmission, glutamatergic-
GO:0060079ISS-excitatory postsynaptic potential-
GO:2000310ISS-regulation of NMDA receptor activity-
GO:2000311ISS-regulation of AMPA receptor activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MAPK8IP2FGF1210854811378392 Affinity Capture-Western
MAPK8IP2FGF1211708611378392 Affinity Capture-Western
MAPK8IP2FGF1310854912244047 Affinity Capture-Western
MAPK8IP2FGF1311708612244047 Affinity Capture-Western
MAPK8IP2IL1B10976910756100 Phenotypic Suppression
MAPK8IP2IL1B11708610756100 Phenotypic Suppression
MAPK8IP2LRP111021510827173 Reconstituted Complex; Two-hybrid
MAPK8IP2LRP111708610827173 Reconstituted Complex; Two-hybrid
MAPK8IP2LRP211021610827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP2LRP211708610827173 12508107 Reconstituted Complex; Two-hybrid
MAPK8IP2MAP3K1011044010490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAP3K1011708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAP3K1111044210490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAP3K1111708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAPK911708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAPK911158710490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAPK1011708610756100 Reconstituted Complex
MAPK8IP2MAPK1011158810756100 Reconstituted Complex
MAPK8IP2MAPK1311708611378392 12244047 Affinity Capture-Western
MAPK8IP2MAPK1311158911378392 12244047 Affinity Capture-Western
MAPK8IP2MAP2K311159212024021 Affinity Capture-Western
MAPK8IP2MAP2K311708612024021 Affinity Capture-Western
MAPK8IP2MAP2K711159510490659 10756100 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAP2K711708610490659 10756100 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2TIAM111293012024021 Affinity Capture-Western
MAPK8IP2TIAM111708612024021 Affinity Capture-Western
MAPK8IP2MAP3K1211356610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAP3K1211708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2LRP811357910827173 Two-hybrid
MAPK8IP2LRP811708610827173 Two-hybrid
MAPK8IP2MAPK8IP111486410490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2MAPK8IP111708610490659 Affinity Capture-Western; Reconstituted Complex
MAPK8IP2PRSS2311708616169070 Two-hybrid
MAPK8IP2PRSS2311627916169070 Two-hybrid
MAPK8IP2MAPK8IP311677410629060 Reconstituted Complex
MAPK8IP2MAPK8IP311708610629060 Reconstituted Complex
MAPK8IP2MAPK8IP211708610490659 Affinity Capture-Western
DUSP16MAPK8IP212332112524447 Affinity Capture-Western
DUSP16MAPK8IP211708612524447 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
MAPK8IP2rs715519, rs916005 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1926555
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070705-326'