AutismKB 2.0

Annotation Details for HEBP2


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Basic Information Top
Gene Symbol:HEBP2 ( C6ORF34B,C6orf34,KIAA1244,PP23,SOUL )
Gene Full Name: heme binding protein 2
Band: 6q24.1
Quick LinksEntrez ID:23593; OMIM: 605825; Uniprot ID:HEBP2_HUMAN; ENSEMBL ID: ENSG00000051620; HGNC ID: 15716
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005737IDA-cytoplasm17098234
GO:0005739IDA-mitochondrion17098234
GO:0035578TAS-azurophil granule lumen-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding16189514
GO ID Evidence Qualifier GO_term References
GO:0010917IMP-negative regulation of mitochondrial membrane potential17098234
GO:0010940IMP-positive regulation of necrotic cell death17098234
GO:0035794IMP-positive regulation of mitochondrial membrane permeability17098234
GO:0043312TAS-neutrophil degranulation-
GO:1901031IMPNOTregulation of response to reactive oxygen species17098234
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HEBP2PDCD611533316189514 Two-hybrid
HEBP2PDCD611712816189514 Two-hybrid
HEBP2LRPPRC11712811827465 Two-hybrid
HEBP2LRPPRC11543211827465 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1860084
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018