AutismKB 2.0

Annotation Details for DAPK2


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Basic Information Top
Gene Symbol:DAPK2 ( DRP-1,DRP1,MGC119312 )
Gene Full Name: death-associated protein kinase 2
Band: 15q22.31
Quick LinksEntrez ID:23604; OMIM: NA; Uniprot ID:DAPK2_HUMAN; ENSEMBL ID: ENSG00000035664; HGNC ID: 2675
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm10376525
GO:0005794IDA-Golgi apparatus-
GO:0031410IEA-cytoplasmic vesicle-
GO:0034423IEA-autophagosome lumen-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004674TAS-protein serine/threonine kinase activity16756490
GO:0005515IPI-protein binding25416956
GO:0005516IDA-calmodulin binding10376525
GO:0005524IDA-ATP binding10376525
GO:0042802IPI-identical protein binding10629061
GO ID Evidence Qualifier GO_term References
GO:0006468IDA-protein phosphorylation10376525
GO:0006915TAS-apoptotic process10629061
GO:0010506TAS-regulation of autophagy16756490
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0018107IBA-peptidyl-threonine phosphorylation-
GO:0035556IDA-intracellular signal transduction10376525
GO:0042981TAS-regulation of apoptotic process16756490
GO:0043276IMP-anoikis18957423
GO:0046777TAS-protein autophosphorylation16756490
GO:0090023IMP-positive regulation of neutrophil chemotaxis24163421
GO:1990266IEA-neutrophil migration-
GO:2000424IMP-positive regulation of eosinophil chemotaxis24163421
GO:2001242IMP-regulation of intrinsic apoptotic signaling pathway10376525
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
DAPK2DAPK211713710629061 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1341297
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018