AutismKB 2.0

Annotation Details for POLA2


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Basic Information Top
Gene Symbol:POLA2 ( FLJ21662,FLJ37250 )
Gene Full Name: polymerase (DNA directed), alpha 2 (70kD subunit)
Band: 11q13.1
Quick LinksEntrez ID:23649; OMIM: NA; Uniprot ID:DPOA2_HUMAN; ENSEMBL ID: ENSG00000014138; HGNC ID: 30073
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005658IBA-alpha DNA polymerase:primase complex-
GO:0005829IDA-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0003674ND-molecular_function-
GO:0003677IEA-DNA binding-
GO:0003887IEA-DNA-directed DNA polymerase activity-
GO:0046982IBA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0000060IEA-protein import into nucleus, translocation-
GO:0000082TAS-G1/S transition of mitotic cell cycle-
GO:0000722TAS-telomere maintenance via recombination-
GO:0006260NAS-DNA replication8223465
GO:0006270IBA-DNA replication initiation-
GO:0006270TAS-DNA replication initiation-
GO:0071897IEA-DNA biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
POLA2PARP11066529518481 Affinity Capture-Western; Far Western
POLA2PARP11171769518481 Affinity Capture-Western; Far Western
POLA2ATP5C111717616169070 Two-hybrid
POLA2ATP5C110699716169070 Two-hybrid
POLA2KLF611717616169070 Two-hybrid
POLA2KLF610771116169070 Two-hybrid
POLA2CPE11717616169070 Two-hybrid
POLA2CPE10775516169070 Two-hybrid
POLA2EZH211717616169070 Two-hybrid
POLA2EZH210844616169070 Two-hybrid
POLA2FGFR311717616169070 Two-hybrid
POLA2FGFR310855216169070 Two-hybrid
POLA2IGFBP311717616169070 Two-hybrid
POLA2IGFBP310970716169070 Two-hybrid
POLA2EIF611717616169070 Two-hybrid
POLA2EIF610989816169070 Two-hybrid
POLA2LRPAP111717616169070 Two-hybrid
POLA2LRPAP111022116169070 Two-hybrid
POLA2NHP2L111717616169070 Two-hybrid
POLA2NHP2L111087416169070 Two-hybrid
POLA2POLA11171768223465 Reconstituted Complex
POLA2POLA11114188223465 Reconstituted Complex
POLA2XPNPEP111717616169070 Two-hybrid
POLA2XPNPEP111334616169070 Two-hybrid
POLA2RAE111717619615732 Affinity Capture-MS
POLA2RAE111405419615732 Affinity Capture-MS
POLA2DHX3411717616169070 Two-hybrid
POLA2DHX3411505616169070 Two-hybrid
POLA2ULK211717616169070 Two-hybrid
POLA2ULK211505816169070 Two-hybrid
POLA2SETDB111520216169070 Two-hybrid
POLA2SETDB111717616169070 Two-hybrid
HELBPOLA212497812181327 Reconstituted Complex
HELBPOLA211717612181327 Reconstituted Complex
C9orf25POLA211717616169070 Two-hybrid
C9orf25POLA212846116169070 Two-hybrid
C8orf30APOLA211717616169070 Two-hybrid
C8orf30APOLA211939816169070 Two-hybrid
RBM23POLA211717616169070 Two-hybrid
RBM23POLA212045016169070 Two-hybrid
DDX24POLA212135316169070 Two-hybrid
DDX24POLA211717616169070 Two-hybrid
AKTIPPOLA211717616169070 Two-hybrid
AKTIPPOLA212215716169070 Two-hybrid
CRELD1POLA211717616169070 Two-hybrid
CRELD1POLA212245816169070 Two-hybrid
STK40POLA211717616169070 Two-hybrid
STK40POLA212381616169070 Two-hybrid
ASCC2POLA211717616169070 Two-hybrid
ASCC2POLA212392116169070 Two-hybrid
PRPF38APOLA211717616169070 Two-hybrid
PRPF38APOLA212438216169070 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:99690
  • Data Attributes: HomoloGene calculated