AutismKB 2.0

Annotation Details for PLXNB2


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Basic Information Top
Gene Symbol:PLXNB2 ( KIAA0315,MM1,Nbla00445,PLEXB2,dJ402G11.3 )
Gene Full Name: plexin B2
Band: 22q13.33
Quick LinksEntrez ID:23654; OMIM: 604293; Uniprot ID:PLXB2_HUMAN; ENSEMBL ID: ENSG00000196576; HGNC ID: 9104
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005887ISS-integral component of plasma membrane-
GO:0009986IDA-cell surface19581412
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15184888
GO:0017154ISS-semaphorin receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0001843ISS-neural tube closure-
GO:0001932ISS-regulation of protein phosphorylation-
GO:0007156IDA-homophilic cell adhesion via plasma membrane adhesion molecules16122393
GO:0007162IBA-negative regulation of cell adhesion-
GO:0007405ISS-neuroblast proliferation-
GO:0007420ISS-brain development-
GO:0008360IBA-regulation of cell shape-
GO:0008360ISS-regulation of cell shape-
GO:0010976IDA-positive regulation of neuron projection development16122393
GO:0043087IBA-regulation of GTPase activity-
GO:0043087ISS-regulation of GTPase activity-
GO:0050772IBA-positive regulation of axonogenesis-
GO:0071526ISS-semaphorin-plexin signaling pathway-
GO:2001222ISS-regulation of neuron migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PLXNB2PLCG111717819805522 Affinity Capture-Western
PLXNB2PLCG111135119805522 Affinity Capture-Western
PLXNB2PTN11717816169070 Two-hybrid
PLXNB2PTN11173116169070 Two-hybrid
PLXNB2ARHGEF1111516412123608 12183458 Affinity Capture-Western; Two-hybrid
PLXNB2ARHGEF1111717812123608 12183458 Affinity Capture-Western; Two-hybrid
PLXNB2ARHGEF1211694512183458 Affinity Capture-Western
PLXNB2ARHGEF1211717812183458 Affinity Capture-Western
RND1PLXNB211811312730235 Two-hybrid
RND1PLXNB211717812730235 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2154239
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-8917'