AutismKB 2.0

Annotation Details for SH3BP4


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Basic Information Top
Gene Symbol:SH3BP4 ( BOG25,TTP )
Gene Full Name: SH3-domain binding protein 4
Band: 2q37.2
Quick LinksEntrez ID:23677; OMIM: 605611; Uniprot ID:SH3B4_HUMAN; ENSEMBL ID: ENSG00000130147; HGNC ID: 10826
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005737IDA-cytoplasm22575674
GO:0005905IEA-clathrin-coated pit-
GO:0030136IEA-clathrin-coated vesicle-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005092IMP-GDP-dissociation inhibitor activity22575674
GO:0005515IPI-protein binding16325581
GO:0017016IPI-Ras GTPase binding22575674
GO:0042802IPI-identical protein binding16325581
GO ID Evidence Qualifier GO_term References
GO:0006897IEA-endocytosis-
GO:0008285IMP-negative regulation of cell proliferation22575674
GO:0010508IMP-positive regulation of autophagy22575674
GO:0030308IMP-negative regulation of cell growth22575674
GO:0032007IMP-negative regulation of TOR signaling22575674
GO:0034260IDA-negative regulation of GTPase activity22575674
GO:0043090IMPNOTamino acid import22575674
GO:0050790IMP-regulation of catalytic activity22575674
GO:0061462IMP-protein localization to lysosome22575674
GO:0071230IMP-cellular response to amino acid stimulus22575674
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SH3BP4SFN10907215778465 Affinity Capture-MS
SH3BP4SFN11719415778465 Affinity Capture-MS
SH3BP4YWHAE11336320936779 Two-hybrid
SH3BP4YWHAE11719420936779 Two-hybrid
SH3BP4YWHAG11336420936779 Two-hybrid
SH3BP4YWHAG11719420936779 Two-hybrid
SH3BP4GIPC111597817353931 Affinity Capture-MS
SH3BP4GIPC111719417353931 Affinity Capture-MS
SH3BP4YWHAQ11719417353931 Affinity Capture-MS
SH3BP4YWHAQ11616817353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2138297
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040303-3'