AutismKB 2.0

Annotation Details for IL17RA


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:IL17RA ( CD217,CDw217,IL-17RA,IL17R,MGC10262,hIL-17R )
Gene Full Name: interleukin 17 receptor A
Band: 22q11.1
Quick LinksEntrez ID:23765; OMIM: 605461; Uniprot ID:I17RA_HUMAN; ENSEMBL ID: ENSG00000177663; HGNC ID: 5985
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576IEA-extracellular region-
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0005887NAS-integral component of plasma membrane9367539
GO ID Evidence Qualifier GO_term References
GO:0005102IEA-receptor binding-
GO:0005515IPI-protein binding21993848
GO:0030368IBA-interleukin-17 receptor activity-
GO:0030368NAS-interleukin-17 receptor activity9367539
GO ID Evidence Qualifier GO_term References
GO:0007166NAS-cell surface receptor signaling pathway9367539
GO:0019221IEA-cytokine-mediated signaling pathway-
GO:0032747IDA-positive regulation of interleukin-23 production21145111
GO:0050832IEA-defense response to fungus-
GO:0071621IEA-granulocyte chemotaxis-
GO:0072537IDA-fibroblast activation21145111
GO:1900017IEA-positive regulation of cytokine production involved in inflammatory response-
GO:2000664IEA-positive regulation of interleukin-5 secretion-
GO:2000667IEA-positive regulation of interleukin-13 secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
IL17RATRAF611726517346928 Affinity Capture-Western
IL17RATRAF611304117346928 Affinity Capture-Western
IL17RAUBC11726517346928 Affinity Capture-Western
IL17RAUBC11316417346928 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
IL17RArs2241049, rs721930 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:107399
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018