AutismKB 2.0

Annotation Details for ARHGAP8


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Basic Information Top
Gene Symbol:ARHGAP8 ( BPGAP1,FLJ20185,PP610 )
Gene Full Name: Rho GTPase activating protein 8
Band: 22q13.31
Quick LinksEntrez ID:23779; OMIM: 609405; Uniprot ID:RHG08_HUMAN; ENSEMBL ID: ENSG00000241484; HGNC ID: 677
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IBA-cytoplasm-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0005096IDA-GTPase activator activity20179103
GO:0005096TAS-GTPase activator activity-
GO:0005515IPI-protein binding20179103
GO ID Evidence Qualifier GO_term References
GO:0007165IEA-signal transduction-
GO:0043547IEA-positive regulation of GTPase activity-
GO:0051056TAS-regulation of small GTPase mediated signal transduction-
GO:0070374IDA-positive regulation of ERK1 and ERK2 cascade20179103
Protein-Protein Interaction Top
No data
Gene Symbol Interactant Interaction ID References Description
ARHGAP8CDC4230090912944407 BPGAP1 interacts with Cdc42.
ARHGAP8RAC129737912944407 BPGAP1 interacts with Rac1.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018