AutismKB 2.0

Annotation Details for IL27


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Basic Information Top
Gene Symbol:IL27 ( IL-27,IL-27A,IL27p28,IL30,MGC71873,p28 )
Gene Full Name: interleukin 27
Band: 16p12.1-p11.2
Quick LinksEntrez ID:246778; OMIM: 608273; Uniprot ID:IL27A_HUMAN; ENSEMBL ID: ENSG00000197272; HGNC ID: 19157
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IBA-extracellular space-
GO:0005615ISS-extracellular space-
GO:0005788TAS-endoplasmic reticulum lumen-
GO ID Evidence Qualifier GO_term References
GO:0005102ISS-receptor binding-
GO:0005125IEA-cytokine activity-
GO:0045523IBA-interleukin-27 receptor binding-
GO:0045523ISS-interleukin-27 receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0002230IEA-positive regulation of defense response to virus by host-
GO:0006954IEA-inflammatory response-
GO:0009617IEA-response to bacterium-
GO:0042129IBA-regulation of T cell proliferation-
GO:0042129ISS-regulation of T cell proliferation-
GO:0045078IDA-positive regulation of interferon-gamma biosynthetic process12734330
GO:0045087IEA-innate immune response-
GO:0045625IDA-regulation of T-helper 1 cell differentiation12734330
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2384409
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018