AutismKB 2.0

Annotation Details for NR5A1


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Basic Information Top
Gene Symbol:NR5A1 ( AD4BP,ELP,FTZ1,FTZF1,POF7,SF-1,SF1 )
Gene Full Name: nuclear receptor subfamily 5, group A, member 1
Band: 9q33.3
Quick LinksEntrez ID:2516; OMIM: 184757; Uniprot ID:STF1_HUMAN; ENSEMBL ID: ENSG00000136931; HGNC ID: 7983
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10567391
GO:0005654TAS-nucleoplasm-
GO:0090575IBA-RNA polymerase II transcription factor complex-
GO:0090575ISS-RNA polymerase II transcription factor complex-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding23610160
GO:0000980ISS-RNA polymerase II distal enhancer sequence-specific DNA binding-
GO:0003677IDA-DNA binding10567391
GO:0003682IBA-chromatin binding-
GO:0003682ISS-chromatin binding-
GO:0003705IDA-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding21412441
GO:0003707IEA-steroid hormone receptor activity-
GO:0003713TAS-transcription coactivator activity8205615
GO:0004879IDA-RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding23610160
GO:0005515IPI-protein binding10567391
GO:0005543IDA-phospholipid binding17664281
GO:0008270IEA-zinc ion binding-
GO:0019899IPI-enzyme binding17664281
GO:0043565IDA-sequence-specific DNA binding27378692
GO ID Evidence Qualifier GO_term References
GO:0001553IEA-luteinization-
GO:0006367TAS-transcription initiation from RNA polymerase II promoter-
GO:0007267TAS-cell-cell signaling10369247
GO:0007530IMP-sex determination24405868
GO:0007538TAS-primary sex determination9590178
GO:0008584IMP-male gonad development27378692
GO:0008585IMP-female gonad development27378692
GO:0009755IBA-hormone-mediated signaling pathway-
GO:0009888IBA-tissue development-
GO:0010259IEA-multicellular organism aging-
GO:0010628IDA-positive regulation of gene expression27378692
GO:0010628IMP-positive regulation of gene expression23610160
GO:0030154IEA-cell differentiation-
GO:0030325IEA-adrenal gland development-
GO:0030522IEA-intracellular receptor signaling pathway-
GO:0042445IEA-hormone metabolic process-
GO:0043401IEA-steroid hormone mediated signaling pathway-
GO:0045944IGI-positive regulation of transcription from RNA polymerase II promoter23610160
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter17664281
GO:0045944ISS-positive regulation of transcription from RNA polymerase II promoter-
GO:0050810TAS-regulation of steroid biosynthetic process10567391
GO:0051457IEA-maintenance of protein location in nucleus-
GO:2000020IDA-positive regulation of male gonad development21412441
GO:2000195IEA-negative regulation of female gonad development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NR5A1NR0B110669511459805 11713202 Reconstituted Complex; Two-hybrid
NR5A1NR0B110879211459805 11713202 Reconstituted Complex; Two-hybrid
NR5A1CREBBP10777710628748 Reconstituted Complex
NR5A1CREBBP10879210628748 Reconstituted Complex
NR5A1CTNNB110788012554773 12861022 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
NR5A1CTNNB110879212554773 12861022 Affinity Capture-Western; Phenotypic Enhancement; Reconstituted Complex; Two-hybrid
NCOA1NR5A11087929328345 Two-hybrid
NCOA1NR5A11142009328345 Two-hybrid
SOX9NR5A11125459774680 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SOX9NR5A11087929774680 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
PITX1NR5A111132410369682 Reconstituted Complex
PITX1NR5A110879210369682 Reconstituted Complex
GATA4NR5A110889610446911 Reconstituted Complex
GATA4NR5A110879210446911 Reconstituted Complex
GTF2BNR5A110921410478848 Reconstituted Complex
GTF2BNR5A110879210478848 Reconstituted Complex
JUNNR5A110992810478848 Reconstituted Complex
JUNNR5A110879210478848 Reconstituted Complex
EDF1NR5A111426010567391 Affinity Capture-Western
EDF1NR5A110879210567391 Affinity Capture-Western
SP1NR5A110879210919277 Reconstituted Complex; Two-hybrid
SP1NR5A111255010919277 Reconstituted Complex; Two-hybrid
NRIP1NR5A111384311459805 12782406 Reconstituted Complex; Two-hybrid
NRIP1NR5A110879211459805 12782406 Reconstituted Complex; Two-hybrid
TRERF1NR5A112091912101186 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TRERF1NR5A110879212101186 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TCF7L2NR5A111279512861022 Phenotypic Enhancement
TCF7L2NR5A110879212861022 Phenotypic Enhancement
ZNF653NR5A112546412920234 Reconstituted Complex; Two-hybrid
ZNF653NR5A110879212920234 Reconstituted Complex; Two-hybrid
CXXC1NR5A111904520211142 Two-hybrid
CXXC1NR5A110879220211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1346833
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010504-1'