AutismKB 2.0

Annotation Details for FUS


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Basic Information Top
Gene Symbol:FUS ( ALS6,FUS1,HNRNPP2,POMP75,TLS )
Gene Full Name: fused in sarcoma
Band: 16p11.2
Quick LinksEntrez ID:2521; OMIM: 137070; Uniprot ID:FUS_HUMAN; ENSEMBL ID: ENSG00000089280; HGNC ID: 4010
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus16365397
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005844IEA-polysome-
GO:0043204IEA-perikaryon-
GO:0044327IEA-dendritic spine head-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0003713IDA-transcription coactivator activity21909421
GO:0003723IDA-RNA binding22658674
GO:0005515IPI-protein binding9774382
GO:0030331IEA-estrogen receptor binding-
GO:0031489IEA-myosin V binding-
GO:0035255IEA-ionotropic glutamate receptor binding-
GO:0042802IPI-identical protein binding23975937
GO:0046872IEA-metal ion binding-
GO:0046965IEA-retinoid X receptor binding-
GO:0046966IEA-thyroid hormone receptor binding-
GO ID Evidence Qualifier GO_term References
GO:0000398TAS-mRNA splicing, via spliceosome-
GO:0006355IEA-regulation of transcription, DNA-templated-
GO:0071277IEA-cellular response to calcium ion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RXRAFUS1087979440806 Reconstituted Complex
RXRAFUS1121689440806 Reconstituted Complex
THRAFUS1087979440806 Reconstituted Complex
THRAFUS1129239440806 Reconstituted Complex
SPI1FUS1087979478924 Affinity Capture-Western; Co-purification; Reconstituted Complex
SPI1FUS1125669478924 Affinity Capture-Western; Co-purification; Reconstituted Complex
SF1FUS1087979660765 Reconstituted Complex
SF1FUS1133689660765 Reconstituted Complex
SRSF10FUS11599010779324 Affinity Capture-Western; Two-hybrid
SRSF10FUS10879710779324 Affinity Capture-Western; Two-hybrid
RELAFUS10879711278855 Affinity Capture-Western; Reconstituted Complex
RELAFUS11190211278855 Affinity Capture-Western; Reconstituted Complex
ILF3FUS10982211438536 Affinity Capture-Western; Two-hybrid
ILF3FUS10879711438536 Affinity Capture-Western; Two-hybrid
PRMT1FUS10951211850402 12183049 16169070 Biochemical Activity; Two-hybrid
PRMT1FUS10879711850402 12183049 16169070 Biochemical Activity; Two-hybrid
YBX1FUS10879712168660 Affinity Capture-Western
YBX1FUS11095912168660 Affinity Capture-Western
SRRM1FUS10879712581738 Affinity Capture-Western
SRRM1FUS11554412581738 Affinity Capture-Western
PTBP2FUS12179612581738 Affinity Capture-Western
PTBP2FUS10879712581738 Affinity Capture-Western
ZMYM2FUS10879715975576 Affinity Capture-MS
ZMYM2FUS11353415975576 Affinity Capture-MS
WBP4FUS11636316055720 Affinity Capture-MS
WBP4FUS10879716055720 Affinity Capture-MS
SARNPFUS12404917196963 Affinity Capture-Western
SARNPFUS10879717196963 Affinity Capture-Western
EIF6FUS10879717353931 Affinity Capture-MS
EIF6FUS10989817353931 Affinity Capture-MS
USF2FUS10879717353931 Affinity Capture-MS
USF2FUS11323817353931 Affinity Capture-MS
OTUB1FUS12075118954305 Affinity Capture-Western
OTUB1FUS10879718954305 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1353633
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040426-1010'