AutismKB 2.0

Annotation Details for RICTOR


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Basic Information Top
Gene Symbol:RICTOR ( DKFZp686B11164,KIAA1999,MGC39830,PIA,mAVO3 )
Gene Full Name: RPTOR independent companion of MTOR, complex 2
Band: 5p13.1
Quick LinksEntrez ID:253260; OMIM: 609022; Uniprot ID:RICTR_HUMAN; ENSEMBL ID: ENSG00000164327; HGNC ID: 28611
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005829TAS-cytosol-
GO:0031932IDA-TORC2 complex15268862
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15467718
GO:0008047IBA-enzyme activator activity-
GO:0019901IPI-protein kinase binding21177249
GO:0043022IEA-ribosome binding-
GO ID Evidence Qualifier GO_term References
GO:0001938IEA-positive regulation of endothelial cell proliferation-
GO:0009790ISS-embryo development-
GO:0010468IEA-regulation of gene expression-
GO:0018105IGI-peptidyl-serine phosphorylation21177249
GO:0030010IBA-establishment of cell polarity-
GO:0030838IEA-positive regulation of actin filament polymerization-
GO:0030950IBA-establishment or maintenance of actin cytoskeleton polarity-
GO:0031295TAS-T cell costimulation-
GO:0031532IMP-actin cytoskeleton reorganization15268862
GO:0031929IEA-TOR signaling-
GO:0032008IMP-positive regulation of TOR signaling15467718
GO:0032956IMP-regulation of actin cytoskeleton organization15467718
GO:0033135IEA-regulation of peptidyl-serine phosphorylation-
GO:0042325IBA-regulation of phosphorylation-
GO:0043085IEA-positive regulation of catalytic activity-
GO:0043087IEA-regulation of GTPase activity-
GO:0048015TAS-phosphatidylinositol-mediated signaling-
GO:0050727IEA-regulation of inflammatory response-
GO:0050731IEA-positive regulation of peptidyl-tyrosine phosphorylation-
GO:0051896IDA-regulation of protein kinase B signaling15718470
GO:0051897IBA-positive regulation of protein kinase B signaling-
GO:2000114IEA-regulation of establishment of cell polarity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
RICTORAKT112896215718470 Reconstituted Complex
RICTORAKT110671015718470 Reconstituted Complex
RICTORMTOR10875715268862 15467718 16183647 16603397 16919458 16962653 17043309 20427287 Affinity Capture-MS; Affinity Capture-Western
RICTORMTOR12896215268862 15467718 16183647 16603397 16919458 16962653 17043309 20427287 Affinity Capture-MS; Affinity Capture-Western
RICTORRPS6KB111211215809305 Reconstituted Complex
RICTORRPS6KB112896215809305 Reconstituted Complex
RICTORRPTOR12158216962653 Affinity Capture-MS
RICTORRPTOR12896216962653 Affinity Capture-MS
RICTORMAPKAP112896216962653 17043309 Affinity Capture-MS; Affinity Capture-Western
RICTORMAPKAP112255116962653 17043309 Affinity Capture-MS; Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1926007
  • Data Attributes: HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-060526-49'