AutismKB 2.0

Annotation Details for FYB


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Basic Information Top
Gene Symbol:FYB ( ADAP,PRO0823,SLAP-130 )
Gene Full Name: FYN binding protein
Band: 5p13.1
Quick LinksEntrez ID:2533; OMIM: 602731; Uniprot ID:FYB_HUMAN; ENSEMBL ID: ENSG00000082074; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005829TAS-cytosol-
GO:0005886IBA-plasma membrane-
GO:0015629TAS-actin cytoskeleton10747096
GO:0030054IEA-cell junction-
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding10747096
GO:0005515IPI-protein binding10409671
GO:0032403IEA-protein complex binding-
GO ID Evidence Qualifier GO_term References
GO:0006468TAS-protein phosphorylation9207119
GO:0006607TAS-NLS-bearing protein import into nucleus9207119
GO:0006955IEA-immune response-
GO:0007165TAS-signal transduction9207119
GO:0008150ND-biological_process-
GO:0035556TAS-intracellular signal transduction9207119
GO:0050852TAS-T cell receptor signaling pathway-
GO:0072659IEA-protein localization to plasma membrane-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FYNFYB1088097504057 9748251 Affinity Capture-Western; Reconstituted Complex
FYNFYB1088107504057 9748251 Affinity Capture-Western; Reconstituted Complex
SKAP1FYB1141849671755 9748251 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SKAP1FYB1088099671755 9748251 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
VASPFYB11325110747096 Affinity Capture-Western
VASPFYB10880910747096 Affinity Capture-Western
WASFYB11329310747096 Affinity Capture-Western
WASFYB10880910747096 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1346327
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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