AutismKB 2.0

Annotation Details for FZD2


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Basic Information Top
Gene Symbol:FZD2 ( - )
Gene Full Name: frizzled homolog 2 (Drosophila)
Band: 17q21.31
Quick LinksEntrez ID:2535; OMIM: 600667; Uniprot ID:FZD2_HUMAN; ENSEMBL ID: ENSG00000180340; HGNC ID: 4040
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IDA-cytoplasm19038973
GO:0005886IDA-plasma membrane18929644
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0016021IEA-integral component of membrane-
GO:0030669TAS-clathrin-coated endocytic vesicle membrane-
GO ID Evidence Qualifier GO_term References
GO:0004930IEA-G-protein coupled receptor activity-
GO:0005515IPI-protein binding25417160
GO:0017147NAS-Wnt-protein binding24431302
GO:0030165IPI-PDZ domain binding19388021
GO:0042813NAS-Wnt-activated receptor activity24431302
GO ID Evidence Qualifier GO_term References
GO:0003149IEA-membranous septum morphogenesis-
GO:0003150IEA-muscular septum morphogenesis-
GO:0003151IEA-outflow tract morphogenesis-
GO:0007186IEA-G-protein coupled receptor signaling pathway-
GO:0007223TAS-Wnt signaling pathway, calcium modulating pathway-
GO:0007608IEA-sensory perception of smell-
GO:0030182ISS-neuron differentiation-
GO:0030825IMP-positive regulation of cGMP metabolic process19946729
GO:0030855IEA-epithelial cell differentiation-
GO:0045893IDA-positive regulation of transcription, DNA-templated18215320
GO:0051091IDA-positive regulation of sequence-specific DNA binding transcription factor activity18929644
GO:0060022IEA-hard palate development-
GO:0060070IDA-canonical Wnt signaling pathway18215320
GO:0060071NAS-Wnt signaling pathway, planar cell polarity pathway24431302
GO:0060071TAS-Wnt signaling pathway, planar cell polarity pathway-
GO:0060119IEA-inner ear receptor cell development-
GO:0090103IEA-cochlea morphogenesis-
GO:0090179IEA-planar cell polarity pathway involved in neural tube closure-
GO:1904886TAS-beta-catenin destruction complex disassembly-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FZD2DLG410808612067714 Two-hybrid
FZD2DLG410881112067714 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1888513
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-990415-224'