AutismKB 2.0

Annotation Details for IFI6


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Basic Information Top
Gene Symbol:IFI6 ( 6-16,FAM14C,G1P3,IFI-6-16,IFI616 )
Gene Full Name: interferon, alpha-inducible protein 6
Band: 1p35.3
Quick LinksEntrez ID:2537; OMIM: 147572; Uniprot ID:IFI6_HUMAN; ENSEMBL ID: ENSG00000126709; HGNC ID: 4054
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion15685448
GO:0005886TAS-plasma membrane-
GO:0016021IEA-integral component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15685448
GO ID Evidence Qualifier GO_term References
GO:0001836IMP-release of cytochrome c from mitochondria15685448
GO:0006955TAS-immune response3017706
GO:0043154IMP-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process15685448
GO:0051902IMP-negative regulation of mitochondrial depolarization15685448
GO:0060337TAS-type I interferon signaling pathway-
GO:2001240IMP-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand15685448
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top

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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018