Annotation Details for GABRA1

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Basic Information Top

Gene Symbol:	GABRA1 ( ECA4,EJM,EJM5 )
Gene Full Name:	gamma-aminobutyric acid (GABA) A receptor, alpha 1
Band:	5q34
Quick Links	Entrez ID:2554; OMIM: 137160; Uniprot ID:GBRA1_HUMAN; ENSEMBL ID: ENSG00000022355; HGNC ID: 4075
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:8 results
Molecular Function:5 results
Biological Process:7 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	ISS	-	integral component of plasma membrane	-
GO:0030054	IEA	-	cell junction	-
GO:0030659	IEA	-	cytoplasmic vesicle membrane	-
GO:0034707	IEA	-	chloride channel complex	-
GO:0045211	IEA	-	postsynaptic membrane	-
GO:1902710	ISS	-	GABA receptor complex	-
GO:1902711	IDA	-	GABA-A receptor complex	9039914

GO ID	Evidence	Qualifier	GO_term	References
GO:0004890	IBA	contributes_to	GABA-A receptor activity	-
GO:0008144	ISS	-	drug binding	-
GO:0016917	ISS	contributes_to	GABA receptor activity	-
GO:0022851	IDA	-	GABA-gated chloride ion channel activity	9039914
GO:1904315	IEA	-	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0006810	TAS	-	transport	2465923
GO:0007214	IEA	-	gamma-aminobutyric acid signaling pathway	-
GO:0034220	TAS	-	ion transmembrane transport	-
GO:0051932	ISS	-	synaptic transmission, GABAergic	-
GO:0060078	IEA	-	regulation of postsynaptic membrane potential	-
GO:0071420	IEA	-	cellular response to histamine	-
GO:1902476	IDA	-	chloride transmembrane transport	9039914

Protein-Protein Interaction

BioGRID:4 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
PRKCD	GABRA1	111566	12091471	Affinity Capture-Western
PRKCD	GABRA1	108828	12091471	Affinity Capture-Western
PRKCG	GABRA1	108828	12091471	Affinity Capture-Western
PRKCG	GABRA1	111568	12091471	Affinity Capture-Western

AlzGene, PDGene and SZGene

Alz Gene:0 results
PD Gene:0 results
SZ Gene:1 results

Gene Symbol	Poly Names	Gene overview in SZGene
GABRA1	GABRA1_371-181A/G, GABRA1_371-471C/T, GABRA1_74 + 9A/T, GABRA1_SA1-3 C/T, rs10056305, rs10064326, rs1037715, rs1129647, rs1157122, rs11575999, rs11745164, rs11948168, rs12658807, rs12658835, rs12659175, rs13171845, rs1350376, rs2279020, rs2290733, rs4254937, rs4260711, rs4311459, rs4340950, rs4367330, rs4464735, rs4478357, rs4605831, rs4608967, rs4632839, rs6862670, rs6873785, rs998754	Gene overview in SZGene

Animal Model

Mouse:1 results
Fruit Fly:1 results

MGI ID: MGI:95613
Data Attributes: MGI curated and HomoloGene calculated