AutismKB 2.0

Annotation Details for GAD2


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Basic Information Top
Gene Symbol:GAD2 ( GAD65,MGC161605,MGC161607 )
Gene Full Name: glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
Band: 10p12.1
Quick LinksEntrez ID:2572; OMIM: 138275; Uniprot ID:DCE2_HUMAN; ENSEMBL ID: ENSG00000136750; HGNC ID: 4093
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000139IEA-Golgi membrane-
GO:0005829IEA-cytosol-
GO:0005886TAS-plasma membrane-
GO:0030054IEA-cell junction-
GO:0030424IEA-axon-
GO:0030672IEA-synaptic vesicle membrane-
GO:0031225IEA-anchored component of membrane-
GO:0042734IEA-presynaptic membrane-
GO:0048471IEA-perinuclear region of cytoplasm-
GO:0060077IEA-inhibitory synapse-
GO:0061202TAS-clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane-
GO ID Evidence Qualifier GO_term References
GO:0004351TAS-glutamate decarboxylase activity-
GO:0005515IPI-protein binding10671565
GO:0016595IEA-glutamate binding-
GO:0030170IEA-pyridoxal phosphate binding-
GO:0046982IEA-protein heterodimerization activity-
GO ID Evidence Qualifier GO_term References
GO:0006540IEA-glutamate decarboxylation to succinate-
GO:0007268TAS-chemical synaptic transmission8954991
GO:0007269TAS-neurotransmitter secretion-
GO:0042136IEA-neurotransmitter biosynthetic process-
GO:0042493IEA-response to drug-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GAD2GAD11088457836456 Affinity Capture-Western
GAD2GAD11088467836456 Affinity Capture-Western
PRKACAGAD211155315147202 Biochemical Activity
PRKACAGAD210884615147202 Biochemical Activity
PRKCEGAD211156715147202 Biochemical Activity
PRKCEGAD210884615147202 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GAD2GAD2_1399C/A, GAD2_243G/A, GAD2_2625A/G, GAD2_29208C/T, GAD2_83897T/A, rs11015008, rs11015015, rs12243037, rs1335547, rs3758446, rs3781117, rs3847378, rs4144102, rs4747547, rs4747548, rs4747549, rs4749105, rs8190764, rs876848, rs913962 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95634
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030909-9'