AutismKB 2.0

Annotation Details for GAK


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Basic Information Top
Gene Symbol:GAK ( FLJ16629,FLJ40395,MGC99654 )
Gene Full Name: cyclin G associated kinase
Band: 4p16.3
Quick LinksEntrez ID:2580; OMIM: 602052; Uniprot ID:GAK_HUMAN; ENSEMBL ID: ENSG00000178950; HGNC ID: 4113
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005794IDA-Golgi apparatus16155256
GO:0005829TAS-cytosol-
GO:0005925IEA-focal adhesion-
GO:0016020IDA-membrane19946888
GO:0031982IDA-vesicle24510904
GO:0043231IDA-intracellular membrane-bounded organelle-
GO:0045202IEA-synapse-
GO:0048471IEA-perinuclear region of cytoplasm-
GO ID Evidence Qualifier GO_term References
GO:0004674IEA-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding22645275
GO:0005524IEA-ATP binding-
GO:0030332ISS-cyclin binding-
GO:0051087TAS-chaperone binding26345367
GO ID Evidence Qualifier GO_term References
GO:0006468IEA-protein phosphorylation-
GO:0006898IMP-receptor-mediated endocytosis16155256
GO:0007029ISS-endoplasmic reticulum organization-
GO:0007030IMP-Golgi organization16155256
GO:0007049IEA-cell cycle-
GO:0010977IDA-negative regulation of neuron projection development24510904
GO:0016191ISS-synaptic vesicle uncoating20160091
GO:0051085TAS-chaperone mediated protein folding requiring cofactor26345367
GO:0061024TAS-membrane organization-
GO:0072318IMP-clathrin coat disassembly16155256
GO:0072583IMP-clathrin-dependent endocytosis16155256
GO:0072600IMP-establishment of protein localization to Golgi16155256
GO:0090002IMP-establishment of protein localization to plasma membrane16155256
GO:0090160IMP-Golgi to lysosome transport16155256
GO:1905224IMP-clathrin-coated pit assembly16155256
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GAKALK10673914968112 Affinity Capture-MS
GAKALK10885314968112 Affinity Capture-MS
GAKCCNG11088539013862 Affinity Capture-Western; Reconstituted Complex
GAKCCNG11073409013862 Affinity Capture-Western; Reconstituted Complex
GAKCDK51088539013862 Affinity Capture-Western
GAKCDK51074559013862 Affinity Capture-Western
AXIN1GAK10885316169070 Two-hybrid
AXIN1GAK11390916169070 Two-hybrid
USO1GAK10885316189514 Two-hybrid
USO1GAK11417316189514 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
No data
Gene Symbol Poly Names Gene overview in PDGene
GAKrs11248051, rs1564282 Gene overview in PDGene
No data
Animal Model Top
  • MGI ID: MGI:2442153
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-041210-358'