AutismKB 2.0

Annotation Details for NIPBL


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Basic Information Top
Gene Symbol:NIPBL ( CDLS,CDLS1,DKFZp434L1319,FLJ11203,FLJ12597,FLJ13354,FLJ13648,FLJ44854,IDN3,IDN3-B,Scc2 )
Gene Full Name: Nipped-B homolog (Drosophila)
Band: 5p13.2
Quick LinksEntrez ID:25836; OMIM: 608667; Uniprot ID:NIPBL_HUMAN; ENSEMBL ID: ENSG00000164190; HGNC ID: 28862
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000785IEA-chromatin-
GO:0005634IDA-nucleus16802858
GO:0005654TAS-nucleoplasm-
GO:0032116IDA-SMC loading complex16682347
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0005515IPI-protein binding16682347
GO:0008022IPI-protein C-terminus binding17577209
GO:0036033IEA-mediator complex binding-
GO:0042826IPI-histone deacetylase binding18854353
GO:0047485IPI-protein N-terminus binding16802858
GO:0070087IPI-chromo shadow domain binding15882967
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter18854353
GO:0001656NAS-metanephros development15146185
GO:0003007IMP-heart morphogenesis8291537
GO:0003151IMP-outflow tract morphogenesis19242925
GO:0006974IMP-cellular response to DNA damage stimulus17468178
GO:0007064IMP-mitotic sister chromatid cohesion16100726
GO:0007420IMP-brain development8291537
GO:0007605IMP-sensory perception of sound15146186
GO:0019827IEA-stem cell population maintenance-
GO:0031065IDA-positive regulation of histone deacetylation18854353
GO:0034088IMP-maintenance of mitotic sister chromatid cohesion16682347
GO:0034613IMP-cellular protein localization17468178
GO:0035115IMP-embryonic forelimb morphogenesis8291537
GO:0035136IMP-forelimb morphogenesis15146186
GO:0035261IMP-external genitalia morphogenesis15146186
GO:0040018IEA-positive regulation of multicellular organism growth-
GO:0042471IMP-ear morphogenesis8291537
GO:0042634IMP-regulation of hair cycle15146186
GO:0045444IEA-fat cell differentiation-
GO:0045778IEA-positive regulation of ossification-
GO:0045892IDA-negative regulation of transcription, DNA-templated18854353
GO:0045944IEA-positive regulation of transcription from RNA polymerase II promoter-
GO:0045995IMP-regulation of embryonic development19242925
GO:0048557IMP-embryonic digestive tract morphogenesis8291537
GO:0048589IMP-developmental growth15146186
GO:0048592IMP-eye morphogenesis8291537
GO:0048638IMP-regulation of developmental growth19242925
GO:0048703IEA-embryonic viscerocranium morphogenesis-
GO:0050890IMP-cognition15146186
GO:0060325IMP-face morphogenesis15146186
GO:0061010IMP-gall bladder development19242925
GO:0061038IMP-uterus morphogenesis19242925
GO:0071481IMP-cellular response to X-ray17468178
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
NIPBLSP10011255515882967 Reconstituted Complex
NIPBLSP10011736315882967 Reconstituted Complex
NIPBLPRSS2311627916169070 Two-hybrid
NIPBLPRSS2311736316169070 Two-hybrid
NIPBLCBX311646315882967 Reconstituted Complex
NIPBLCBX311736315882967 Reconstituted Complex
NIPBLCBX511703015882967 Affinity Capture-MS; Affinity Capture-Western; Protein-peptide
NIPBLCBX511736315882967 Affinity Capture-MS; Affinity Capture-Western; Protein-peptide
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1913976
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-6070'