AutismKB 2.0

Annotation Details for AMBP


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Basic Information Top
Gene Symbol:AMBP ( A1M,EDC1,HCP,HI30,IATIL,ITI,ITIL,ITILC,UTI )
Gene Full Name: alpha-1-microglobulin/bikunin precursor
Band: 9q32
Quick LinksEntrez ID:259; OMIM: 176870; Uniprot ID:AMBP_HUMAN; ENSEMBL ID: ENSG00000106927; HGNC ID: 453
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576NAS-extracellular region11877257
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space16502470
GO:0005886IDA-plasma membrane12817471
GO:0009986IEA-cell surface-
GO:0043231IEA-intracellular membrane-bounded organelle-
GO:0070062IDA-extracellular exosome19056867
GO:0072562IDA-blood microparticle22516433
GO ID Evidence Qualifier GO_term References
GO:0004867TAS-serine-type endopeptidase inhibitor activity12817471
GO:0005515IPI-protein binding16364318
GO:0019855NAS-calcium channel inhibitor activity12817471
GO:0019862IDA-IgA binding11877257
GO:0020037IDA-heme binding11877257
GO:0036094IEA-small molecule binding-
GO:0042803IPI-protein homodimerization activity11883904
GO:0046904NAS-calcium oxalate binding14516400
GO ID Evidence Qualifier GO_term References
GO:0006898TAS-receptor-mediated endocytosis-
GO:0007155NAS-cell adhesion9570066
GO:0007565NAS-female pregnancy10097787
GO:0010951IEA-negative regulation of endopeptidase activity-
GO:0016032IEA-viral process-
GO:0018298IEA-protein-chromophore linkage-
GO:0030163IEA-protein catabolic process-
GO:0042167NAS-heme catabolic process11877257
GO:0046329TAS-negative regulation of JNK cascade12817471
GO:0050777NAS-negative regulation of immune response10097787
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
AMBPA2M1065241697852 7519849 Affinity Capture-Western
AMBPA2M1067571697852 7519849 Affinity Capture-Western
AMBPALB1067579183005 Affinity Capture-Western
AMBPALB1067159183005 Affinity Capture-Western
CD79AAMBP1074116196366 9183005 Affinity Capture-Western; Co-purification
CD79AAMBP1067576196366 9183005 Affinity Capture-Western; Co-purification
FN1AMBP1086217519849 Affinity Capture-Western
FN1AMBP1067577519849 Affinity Capture-Western
AMBPAMBP1067579183005 11883904 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:88002
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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