Annotation Details for NCR3

View Evidences	View Variants	View Annotations

Basic Information Top

Gene Symbol:	NCR3 ( 1C7,CD337,LY117,MALS,NKp30 )
Gene Full Name:	natural cytotoxicity triggering receptor 3
Band:	6p21.33
Quick Links	Entrez ID:259197; OMIM: 611550; Uniprot ID:NCTR3_HUMAN; ENSEMBL ID: ENSG00000204475; HGNC ID: 19077
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:5 results
Biological Process:12 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005886	TAS	-	plasma membrane	-
GO:0005887	TAS	-	integral component of plasma membrane	7590964
GO:0005913	IBA	-	cell-cell adherens junction	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0004872	IBA	-	receptor activity	-
GO:0005102	IBA	-	receptor binding	-
GO:0005515	IPI	-	protein binding	18852879
GO:0042803	IBA	-	protein homodimerization activity	-
GO:0050839	IBA	-	cell adhesion molecule binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0002429	IDA	-	immune response-activating cell surface receptor signaling pathway	18852879
GO:0002860	IBA	-	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	-
GO:0006954	NAS	-	inflammatory response	10941844
GO:0006955	NAS	-	immune response	10941844
GO:0007156	IBA	-	homophilic cell adhesion via plasma membrane adhesion molecules	-
GO:0007157	IBA	-	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	-
GO:0008037	TAS	-	cell recognition	16304049
GO:0030101	IDA	-	natural killer cell activation	18852879
GO:0042271	IBA	-	susceptibility to natural killer cell mediated cytotoxicity	-
GO:0045954	IMP	-	positive regulation of natural killer cell mediated cytotoxicity	16304049
GO:0050776	TAS	-	regulation of immune response	-
GO:0060370	IBA	-	susceptibility to T cell mediated cytotoxicity	-

Protein-Protein Interaction

BioGRID:2 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
NCR3	CD59	129224	14635045	Affinity Capture-Western
NCR3	CD59	107404	14635045	Affinity Capture-Western

AlzGene, PDGene and SZGene

Alz Gene:0 results
PD Gene:0 results
SZ Gene:1 results

Gene Symbol	Poly Names	Gene overview in SZGene
NCR3	rs2515919, rs2736191, rs2857595	Gene overview in SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:2149332
Data Attributes: MGI curated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved