AutismKB 2.0

Annotation Details for ASPM


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Basic Information Top
Gene Symbol:ASPM ( ASP,Calmbp1,DKFZp686N06184,FLJ10517,FLJ10549,FLJ43117,MCPH5 )
Gene Full Name: asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
Band: 1q31.3
Quick LinksEntrez ID:259266; OMIM: 605481; Uniprot ID:ASPM_HUMAN; ENSEMBL ID: ENSG00000066279; HGNC ID: 19048
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21044324
GO:0005737IEA-cytoplasm-
GO:0030496IEA-midbody-
GO:0036449IDA-microtubule minus-end21044324
GO:0072687IEA-meiotic spindle-
GO:0097431IDA-mitotic spindle pole15972725
GO ID Evidence Qualifier GO_term References
GO:0005516IEA-calmodulin binding-
GO ID Evidence Qualifier GO_term References
GO:0001764IEA-neuron migration-
GO:0002052IEA-positive regulation of neuroblast proliferation-
GO:0007051IMP-spindle organization21044324
GO:0007283IEA-spermatogenesis-
GO:0008584IEA-male gonad development-
GO:0021873IEA-forebrain neuroblast division-
GO:0021987IEA-cerebral cortex development-
GO:0045665IEA-negative regulation of neuron differentiation-
GO:0045769IEA-negative regulation of asymmetric cell division-
GO:0048477IEA-oogenesis-
GO:0048589IEA-developmental growth-
GO:0051445IEA-regulation of meiotic cell cycle-
GO:0051653IMP-spindle localization21044324
GO:0051661IEA-maintenance of centrosome location-
GO:0090263IEA-positive regulation of canonical Wnt signaling pathway-
GO:0090306IEA-spindle assembly involved in meiosis-
GO:0097150IEA-neuronal stem cell population maintenance-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
ASPMTP5311301020308539 Affinity Capture-Western
ASPMTP5312923620308539 Affinity Capture-Western
ASPMTP7311301420308539 Affinity Capture-Western
ASPMTP7312923620308539 Affinity Capture-Western
ASPMTP6311418120308539 Affinity Capture-Western
ASPMTP6312923620308539 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
ASPMrs1018668, rs3762271, rs41310927, rs4915337, rs9726778 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1334448
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050208-620'