AutismKB 2.0

Annotation Details for PVRL3


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Basic Information Top
Gene Symbol:PVRL3 ( CD113,CDw113,DKFZp566B0846,FLJ90624,PPR3,PRR3,PVRR3,nectin-3 )
Gene Full Name: poliovirus receptor-related 3
Band: 3q13
Quick LinksEntrez ID:25945; OMIM: 607147; Uniprot ID:PVRL3_HUMAN; ENSEMBL ID: ENSG00000177707; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886ISS-plasma membrane-
GO:0005886TAS-plasma membrane-
GO:0005887IBA-integral component of plasma membrane-
GO:0005913IBA-cell-cell adherens junction-
GO:0043296IEA-apical junction complex-
GO:0044291IEA-cell-cell contact zone-
GO:0045211IEA-postsynaptic membrane-
GO ID Evidence Qualifier GO_term References
GO:0004872IBA-receptor activity-
GO:0005102IBA-receptor binding-
GO:0005515IPI-protein binding19011627
GO:0042803IBA-protein homodimerization activity-
GO:0042803ISS-protein homodimerization activity-
GO:0046982IEA-protein heterodimerization activity-
GO:0050839IPI-cell adhesion molecule binding12438620
GO ID Evidence Qualifier GO_term References
GO:0002089IEA-lens morphogenesis in camera-type eye-
GO:0007156IBA-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007156ISS-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007157IBA-heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules-
GO:0007286IEA-spermatid development-
GO:0008037IBA-cell recognition-
GO:0009566IEA-fertilization-
GO:0016337IEA-single organismal cell-cell adhesion-
GO:0034332TAS-adherens junction organization-
GO:0060042IEA-retina morphogenesis in camera-type eye-
GO:1902414IEA-protein localization to cell junction-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PVRL3MLLT411744110744716 11024295 Reconstituted Complex
PVRL3MLLT411044710744716 11024295 Reconstituted Complex
PVRL3PVR11744112759359 Reconstituted Complex
PVRL3PVR11177512759359 Reconstituted Complex
PVRL3PVRL311744110744716 Co-purification
PARD3PVRL312113412515806 Affinity Capture-Western; Reconstituted Complex
PARD3PVRL311744112515806 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1930171
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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