AutismKB 2.0

Annotation Details for SH2B1


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Basic Information Top
Gene Symbol:SH2B1 ( DKFZp547G1110,FLJ30542,KIAA1299,PSM,SH2B )
Gene Full Name: SH2B adaptor protein 1
Band: 16p11.2
Quick LinksEntrez ID:25970; OMIM: 608937; Uniprot ID:SH2B1_HUMAN; ENSEMBL ID: ENSG00000178188; HGNC ID: 30417
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IEA-nucleus-
GO:0005829TAS-cytosol-
GO:0016020IEA-membrane-
GO ID Evidence Qualifier GO_term References
GO:0004871IEA-signal transducer activity-
GO:0005515IPI-protein binding9742218
GO:0035591IEA-signaling adaptor activity-
GO ID Evidence Qualifier GO_term References
GO:0007596TAS-blood coagulation-
GO:0009967IEA-positive regulation of signal transduction-
GO:0030032IEA-lamellipodium assembly-
GO:0035556IEA-intracellular signal transduction-
GO:0045840IEA-positive regulation of mitotic nuclear division-
GO:2000278IEA-regulation of DNA biosynthetic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SH2B1FGFR310855211827956 Affinity Capture-Western
SH2B1GRB21091429742218 9856458 Affinity Capture-Western; Reconstituted Complex
SH2B1GRB21174559742218 9856458 Affinity Capture-Western; Reconstituted Complex
SH2B1INSR1098549742218 10594240 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SH2B1INSR1174559742218 10594240 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SH2B1JAK21099209343427 12370803 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SH2B1JAK21174559343427 12370803 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
SH2B1NTRK11109699856458 10708759 Affinity Capture-Western; Two-hybrid
SH2B1NTRK11174559856458 10708759 Affinity Capture-Western; Two-hybrid
SH2B1NTRK211097012074588 Two-hybrid
SH2B1NTRK211745512074588 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1201407
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-070209-188'