AutismKB 2.0

Annotation Details for CHD5


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Basic Information Top
Gene Symbol:CHD5 ( DKFZp434N231,KIAA0444 )
Gene Full Name: chromodomain helicase DNA binding protein 5
Band: 1p36.31
Quick LinksEntrez ID:26038; OMIM: 610771; Uniprot ID:CHD5_HUMAN; ENSEMBL ID: ENSG00000116254; HGNC ID: 16816
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000792ISS-heterochromatin-
GO:0005634IDA-nucleus21931736
GO:0005654IDA-nucleoplasm-
GO:0005829IDA-cytosol-
GO:0016020IDA-membrane19946888
GO:0016581ISS-NuRD complex-
GO:0016607IDA-nuclear speck-
GO ID Evidence Qualifier GO_term References
GO:0003677IEA-DNA binding-
GO:0004386IEA-helicase activity-
GO:0005524IEA-ATP binding-
GO:0046872IEA-metal ion binding-
GO:0061628IDA-H3K27me3 modified histone binding23948251
GO ID Evidence Qualifier GO_term References
GO:0006351IEA-transcription, DNA-templated-
GO:0008285ISS-negative regulation of cell proliferation-
GO:0021895ISS-cerebral cortex neuron differentiation-
GO:0035093ISS-spermatogenesis, exchange of chromosomal proteins-
GO:0043967ISS-histone H4 acetylation-
GO:0060850IMP-regulation of transcription involved in cell fate commitment23948251
GO:0098532IMP-histone H3-K27 trimethylation23948251
GO:1901798ISS-positive regulation of signal transduction by p53 class mediator-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018