Annotation Details for GATA1


Gene Symbol: | GATA1 ( ERYF1,GATA-1,GF-1,GF1,NFE1,XLTT ) |
---|---|
Gene Full Name: | GATA binding protein 1 (globin transcription factor 1) |
Band: | Xp11.23 |
Quick Links | Entrez ID:2623; OMIM: 305371; Uniprot ID:GATA1_HUMAN; ENSEMBL ID: ENSG00000102145; HGNC ID: 4170 |
Relate to Another Database: | SFARIGene; denovo-db |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0005634 | IDA | - | nucleus | 2467208 |
GO:0005654 | TAS | - | nucleoplasm | - |
GO:0005667 | IDA | - | transcription factor complex | 15920471 |
GO:0017053 | IDA | - | transcriptional repressor complex | 15920471 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000976 | IMP | - | transcription regulatory region sequence-specific DNA binding | 10700180 |
GO:0000977 | IDA | - | RNA polymerase II regulatory region sequence-specific DNA binding | 2467208 |
GO:0000978 | IEA | - | RNA polymerase II core promoter proximal region sequence-specific DNA binding | - |
GO:0000979 | IMP | - | RNA polymerase II core promoter sequence-specific DNA binding | 20133935 |
GO:0001047 | IDA | - | core promoter binding | 24245781 |
GO:0001077 | IEA | - | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | - |
GO:0001078 | IDA | - | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding | 15920471 |
GO:0001085 | IPI | - | RNA polymerase II transcription factor binding | 11675338 |
GO:0001158 | IEA | - | enhancer sequence-specific DNA binding | - |
GO:0001228 | IBA | - | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding | - |
GO:0002039 | IEA | - | p53 binding | - |
GO:0003677 | IDA | - | DNA binding | 8628290 |
GO:0003700 | IDA | - | transcription factor activity, sequence-specific DNA binding | 2467208 |
GO:0005515 | IPI | - | protein binding | 11418466 |
GO:0008270 | IEA | - | zinc ion binding | - |
GO:0008301 | IEA | - | DNA binding, bending | - |
GO:0031490 | IDA | - | chromatin DNA binding | 22235304 |
GO:0043565 | IMP | - | sequence-specific DNA binding | 12200364 |
GO:0070742 | IPI | - | C2H2 zinc finger domain binding | 12483298 |
GO ID | Evidence | Qualifier | GO_term | References |
---|---|---|---|---|
GO:0000122 | IDA | - | negative regulation of transcription from RNA polymerase II promoter | 22235304 |
GO:0001701 | IEA | - | in utero embryonic development | - |
GO:0006366 | IDA | - | transcription from RNA polymerase II promoter | 2467208 |
GO:0007267 | IEA | - | cell-cell signaling | - |
GO:0007596 | TAS | - | blood coagulation | - |
GO:0008285 | IEA | - | negative regulation of cell proliferation | - |
GO:0008584 | IMP | - | male gonad development | 10700180 |
GO:0010559 | IMP | - | regulation of glycoprotein biosynthetic process | 15701726 |
GO:0010724 | IDA | - | regulation of definitive erythrocyte differentiation | 12200364 |
GO:0010725 | IEA | - | regulation of primitive erythrocyte differentiation | - |
GO:0030218 | IEP | - | erythrocyte differentiation | 7678994 |
GO:0030219 | IMP | - | megakaryocyte differentiation | 10700180 |
GO:0030220 | IMP | - | platelet formation | 10700180 |
GO:0030221 | IEP | - | basophil differentiation | 7678994 |
GO:0030222 | IEP | - | eosinophil differentiation | 8507862 |
GO:0030502 | IEA | - | negative regulation of bone mineralization | - |
GO:0033690 | IEA | - | positive regulation of osteoblast proliferation | - |
GO:0035162 | IEA | - | embryonic hemopoiesis | - |
GO:0035854 | IDA | - | eosinophil fate commitment | 12045236 |
GO:0043066 | IMP | - | negative regulation of apoptotic process | 17167422 |
GO:0045648 | IMP | - | positive regulation of erythrocyte differentiation | 17167422 |
GO:0045893 | IDA | - | positive regulation of transcription, DNA-templated | 24245781 |
GO:0045944 | IDA | - | positive regulation of transcription from RNA polymerase II promoter | 12200364 |
GO:0045944 | IMP | - | positive regulation of transcription from RNA polymerase II promoter | 20133935 |
GO:0048821 | IMP | - | erythrocyte development | 10700180 |
GO:0048873 | IEA | - | homeostasis of number of cells within a tissue | - |
GO:0050731 | IMP | - | positive regulation of peptidyl-tyrosine phosphorylation | 15701726 |
GO:0070527 | IMP | - | platelet aggregation | 15701726 |
GO:0071733 | ISS | - | transcriptional activation by promoter-enhancer looping | - |
GO:0097028 | IEA | - | dendritic cell differentiation | - |
GO:0097067 | IDA | - | cellular response to thyroid hormone stimulus | 19375645 |
GO:2000678 | IDA | - | negative regulation of transcription regulatory region DNA binding | 15920471 |
GO:2001240 | IMP | - | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand | 17167422 |
Gene Symbol | Interactant | Interaction ID | References | Description |
---|---|---|---|---|
GATA1 | CREBBP | 108893 | 12496368 | Reconstituted Complex |
GATA1 | CREBBP | 107777 | 12496368 | Reconstituted Complex |
GATA1 | FLI1 | 108893 | 12556498 12724402 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
GATA1 | FLI1 | 108602 | 12556498 12724402 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
TAL1 | GATA1 | 112749 | 7568177 16407974 | Affinity Capture-MS; Two-hybrid |
TAL1 | GATA1 | 108893 | 7568177 16407974 | Affinity Capture-MS; Two-hybrid |
LMO2 | GATA1 | 108893 | 7568177 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
LMO2 | GATA1 | 110191 | 7568177 | Affinity Capture-Western; Reconstituted Complex; Two-hybrid |
ZFPM2 | GATA1 | 108893 | 10438528 | Reconstituted Complex; Two-hybrid |
ZFPM2 | GATA1 | 116986 | 10438528 | Reconstituted Complex; Two-hybrid |
SMARCA4 | GATA1 | 112481 | 11018012 | Reconstituted Complex |
SMARCA4 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
SMARCB1 | GATA1 | 112482 | 11018012 | Reconstituted Complex |
SMARCB1 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
SMARCC1 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
SMARCC1 | GATA1 | 112483 | 11018012 | Reconstituted Complex |
SMARCC2 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
SMARCC2 | GATA1 | 112485 | 11018012 | Reconstituted Complex |
SMARCD1 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
SMARCD1 | GATA1 | 112486 | 11018012 | Reconstituted Complex |
SMARCE1 | GATA1 | 112489 | 11018012 | Reconstituted Complex |
SMARCE1 | GATA1 | 108893 | 11018012 | Reconstituted Complex |
ARID1A | GATA1 | 108893 | 11018012 | Reconstituted Complex |
ARID1A | GATA1 | 113894 | 11018012 | Reconstituted Complex |
SP1 | GATA1 | 108893 | 12239153 | Reconstituted Complex |
SP1 | GATA1 | 112550 | 12239153 | Reconstituted Complex |
ZBTB16 | GATA1 | 113498 | 12242665 | Affinity Capture-Western |
ZBTB16 | GATA1 | 108893 | 12242665 | Affinity Capture-Western |
HDAC1 | GATA1 | 108893 | 14668799 | Affinity Capture-Western |
HDAC1 | GATA1 | 109315 | 14668799 | Affinity Capture-Western |
HDAC5 | GATA1 | 108893 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
HDAC5 | GATA1 | 115331 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
HDAC3 | GATA1 | 108893 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
HDAC3 | GATA1 | 114368 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
HDAC4 | GATA1 | 108893 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
HDAC4 | GATA1 | 115106 | 14668799 | Affinity Capture-Western; Reconstituted Complex |
SKI | GATA1 | 108893 | 15542823 | Affinity Capture-Western |
SKI | GATA1 | 112388 | 15542823 | Affinity Capture-Western |
NME1 | GATA1 | 108893 | 16631833 | Affinity Capture-Western |
NME1 | GATA1 | 110894 | 16631833 | Affinity Capture-Western |
MED14 | GATA1 | 108893 | 17132730 | Affinity Capture-Western |
MED14 | GATA1 | 114699 | 17132730 | Affinity Capture-Western |
MED17 | GATA1 | 108893 | 17132730 | Affinity Capture-Western |
MED17 | GATA1 | 114830 | 17132730 | Affinity Capture-Western |
MED1 | GATA1 | 111465 | 17132730 | Affinity Capture-Western; Reconstituted Complex |
MED1 | GATA1 | 108893 | 17132730 | Affinity Capture-Western; Reconstituted Complex |
IKZF1 | GATA1 | 108893 | 19114560 | Affinity Capture-Western |
IKZF1 | GATA1 | 115604 | 19114560 | Affinity Capture-Western |
ZFPM1 | GATA1 | 108893 | 19513100 | Affinity Capture-Western |
ZFPM1 | GATA1 | 127806 | 19513100 | Affinity Capture-Western |
RAI1 | GATA1 | 115966 | 20211142 | Two-hybrid |
RAI1 | GATA1 | 108893 | 20211142 | Two-hybrid |
TRIM29 | GATA1 | 117177 | 20211142 | Two-hybrid |
TRIM29 | GATA1 | 108893 | 20211142 | Two-hybrid |
ZZZ3 | GATA1 | 108893 | 20211142 | Two-hybrid |
ZZZ3 | GATA1 | 117482 | 20211142 | Two-hybrid |
TAX1BP3 | GATA1 | 108893 | 20211142 | Two-hybrid |
TAX1BP3 | GATA1 | 119061 | 20211142 | Two-hybrid |
TAF7 | GATA1 | 108893 | 20211142 | Two-hybrid |
TAF7 | GATA1 | 112742 | 20211142 | Two-hybrid |
TRIM25 | GATA1 | 113500 | 20211142 | Two-hybrid |
TRIM25 | GATA1 | 108893 | 20211142 | Two-hybrid |
ZBTB22 | GATA1 | 114695 | 20211142 | Two-hybrid |
ZBTB22 | GATA1 | 108893 | 20211142 | Two-hybrid |
No data |
No data |
- MGI ID: MGI:95661
- Data Attributes: MGI curated and HomoloGene calculated
- ZFIN ID: ZDB-GENE-081104-43