AutismKB 2.0

Annotation Details for GATA1


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Basic Information Top
Gene Symbol:GATA1 ( ERYF1,GATA-1,GF-1,GF1,NFE1,XLTT )
Gene Full Name: GATA binding protein 1 (globin transcription factor 1)
Band: Xp11.23
Quick LinksEntrez ID:2623; OMIM: 305371; Uniprot ID:GATA1_HUMAN; ENSEMBL ID: ENSG00000102145; HGNC ID: 4170
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus2467208
GO:0005654TAS-nucleoplasm-
GO:0005667IDA-transcription factor complex15920471
GO:0017053IDA-transcriptional repressor complex15920471
GO ID Evidence Qualifier GO_term References
GO:0000976IMP-transcription regulatory region sequence-specific DNA binding10700180
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding2467208
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0000979IMP-RNA polymerase II core promoter sequence-specific DNA binding20133935
GO:0001047IDA-core promoter binding24245781
GO:0001077IEA-transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding-
GO:0001078IDA-transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding15920471
GO:0001085IPI-RNA polymerase II transcription factor binding11675338
GO:0001158IEA-enhancer sequence-specific DNA binding-
GO:0001228IBA-transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding-
GO:0002039IEA-p53 binding-
GO:0003677IDA-DNA binding8628290
GO:0003700IDA-transcription factor activity, sequence-specific DNA binding2467208
GO:0005515IPI-protein binding11418466
GO:0008270IEA-zinc ion binding-
GO:0008301IEA-DNA binding, bending-
GO:0031490IDA-chromatin DNA binding22235304
GO:0043565IMP-sequence-specific DNA binding12200364
GO:0070742IPI-C2H2 zinc finger domain binding12483298
GO ID Evidence Qualifier GO_term References
GO:0000122IDA-negative regulation of transcription from RNA polymerase II promoter22235304
GO:0001701IEA-in utero embryonic development-
GO:0006366IDA-transcription from RNA polymerase II promoter2467208
GO:0007267IEA-cell-cell signaling-
GO:0007596TAS-blood coagulation-
GO:0008285IEA-negative regulation of cell proliferation-
GO:0008584IMP-male gonad development10700180
GO:0010559IMP-regulation of glycoprotein biosynthetic process15701726
GO:0010724IDA-regulation of definitive erythrocyte differentiation12200364
GO:0010725IEA-regulation of primitive erythrocyte differentiation-
GO:0030218IEP-erythrocyte differentiation7678994
GO:0030219IMP-megakaryocyte differentiation10700180
GO:0030220IMP-platelet formation10700180
GO:0030221IEP-basophil differentiation7678994
GO:0030222IEP-eosinophil differentiation8507862
GO:0030502IEA-negative regulation of bone mineralization-
GO:0033690IEA-positive regulation of osteoblast proliferation-
GO:0035162IEA-embryonic hemopoiesis-
GO:0035854IDA-eosinophil fate commitment12045236
GO:0043066IMP-negative regulation of apoptotic process17167422
GO:0045648IMP-positive regulation of erythrocyte differentiation17167422
GO:0045893IDA-positive regulation of transcription, DNA-templated24245781
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter12200364
GO:0045944IMP-positive regulation of transcription from RNA polymerase II promoter20133935
GO:0048821IMP-erythrocyte development10700180
GO:0048873IEA-homeostasis of number of cells within a tissue-
GO:0050731IMP-positive regulation of peptidyl-tyrosine phosphorylation15701726
GO:0070527IMP-platelet aggregation15701726
GO:0071733ISS-transcriptional activation by promoter-enhancer looping-
GO:0097028IEA-dendritic cell differentiation-
GO:0097067IDA-cellular response to thyroid hormone stimulus19375645
GO:2000678IDA-negative regulation of transcription regulatory region DNA binding15920471
GO:2001240IMP-negative regulation of extrinsic apoptotic signaling pathway in absence of ligand17167422
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GATA1CREBBP10889312496368 Reconstituted Complex
GATA1CREBBP10777712496368 Reconstituted Complex
GATA1FLI110889312556498 12724402 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
GATA1FLI110860212556498 12724402 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TAL1GATA11127497568177 16407974 Affinity Capture-MS; Two-hybrid
TAL1GATA11088937568177 16407974 Affinity Capture-MS; Two-hybrid
LMO2GATA11088937568177 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
LMO2GATA11101917568177 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ZFPM2GATA110889310438528 Reconstituted Complex; Two-hybrid
ZFPM2GATA111698610438528 Reconstituted Complex; Two-hybrid
SMARCA4GATA111248111018012 Reconstituted Complex
SMARCA4GATA110889311018012 Reconstituted Complex
SMARCB1GATA111248211018012 Reconstituted Complex
SMARCB1GATA110889311018012 Reconstituted Complex
SMARCC1GATA110889311018012 Reconstituted Complex
SMARCC1GATA111248311018012 Reconstituted Complex
SMARCC2GATA110889311018012 Reconstituted Complex
SMARCC2GATA111248511018012 Reconstituted Complex
SMARCD1GATA110889311018012 Reconstituted Complex
SMARCD1GATA111248611018012 Reconstituted Complex
SMARCE1GATA111248911018012 Reconstituted Complex
SMARCE1GATA110889311018012 Reconstituted Complex
ARID1AGATA110889311018012 Reconstituted Complex
ARID1AGATA111389411018012 Reconstituted Complex
SP1GATA110889312239153 Reconstituted Complex
SP1GATA111255012239153 Reconstituted Complex
ZBTB16GATA111349812242665 Affinity Capture-Western
ZBTB16GATA110889312242665 Affinity Capture-Western
HDAC1GATA110889314668799 Affinity Capture-Western
HDAC1GATA110931514668799 Affinity Capture-Western
HDAC5GATA110889314668799 Affinity Capture-Western; Reconstituted Complex
HDAC5GATA111533114668799 Affinity Capture-Western; Reconstituted Complex
HDAC3GATA110889314668799 Affinity Capture-Western; Reconstituted Complex
HDAC3GATA111436814668799 Affinity Capture-Western; Reconstituted Complex
HDAC4GATA110889314668799 Affinity Capture-Western; Reconstituted Complex
HDAC4GATA111510614668799 Affinity Capture-Western; Reconstituted Complex
SKIGATA110889315542823 Affinity Capture-Western
SKIGATA111238815542823 Affinity Capture-Western
NME1GATA110889316631833 Affinity Capture-Western
NME1GATA111089416631833 Affinity Capture-Western
MED14GATA110889317132730 Affinity Capture-Western
MED14GATA111469917132730 Affinity Capture-Western
MED17GATA110889317132730 Affinity Capture-Western
MED17GATA111483017132730 Affinity Capture-Western
MED1GATA111146517132730 Affinity Capture-Western; Reconstituted Complex
MED1GATA110889317132730 Affinity Capture-Western; Reconstituted Complex
IKZF1GATA110889319114560 Affinity Capture-Western
IKZF1GATA111560419114560 Affinity Capture-Western
ZFPM1GATA110889319513100 Affinity Capture-Western
ZFPM1GATA112780619513100 Affinity Capture-Western
RAI1GATA111596620211142 Two-hybrid
RAI1GATA110889320211142 Two-hybrid
TRIM29GATA111717720211142 Two-hybrid
TRIM29GATA110889320211142 Two-hybrid
ZZZ3GATA110889320211142 Two-hybrid
ZZZ3GATA111748220211142 Two-hybrid
TAX1BP3GATA110889320211142 Two-hybrid
TAX1BP3GATA111906120211142 Two-hybrid
TAF7GATA110889320211142 Two-hybrid
TAF7GATA111274220211142 Two-hybrid
TRIM25GATA111350020211142 Two-hybrid
TRIM25GATA110889320211142 Two-hybrid
ZBTB22GATA111469520211142 Two-hybrid
ZBTB22GATA110889320211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95661
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-081104-43'