AutismKB 2.0

Annotation Details for FBXL5


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Basic Information Top
Gene Symbol:FBXL5 ( FBL4,FBL5,FLR1 )
Gene Full Name: F-box and leucine-rich repeat protein 5
Band: 4p15.32
Quick LinksEntrez ID:26234; OMIM: 605655; Uniprot ID:FBXL5_HUMAN; ENSEMBL ID: ENSG00000118564; HGNC ID: 13602
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000151NAS-ubiquitin ligase complex10531035
GO:0005829TAS-cytosol-
GO:0019005IDA-SCF ubiquitin ligase complex19762596
GO:0048471IDA-perinuclear region of cytoplasm17532294
GO ID Evidence Qualifier GO_term References
GO:0004842EXP-ubiquitin-protein transferase activity19028597
GO:0004842NAS-ubiquitin-protein transferase activity10531035
GO:0004842TAS-ubiquitin-protein transferase activity-
GO:0005506IDA-iron ion binding19762596
GO:0005515IPI-protein binding17532294
GO ID Evidence Qualifier GO_term References
GO:0000209TAS-protein polyubiquitination-
GO:0006879TAS-cellular iron ion homeostasis-
GO:0016567IDA-protein ubiquitination17532294
GO:0016567NAS-protein ubiquitination10531035
GO:0031146IDA-SCF-dependent proteasomal ubiquitin-dependent protein catabolic process17532294
GO:0043687TAS-post-translational protein modification-
GO:0055072IEP-iron ion homeostasis19762597
GO:0055072IMP-iron ion homeostasis19762596
GO:1903364IEA-positive regulation of cellular protein catabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
FBXL5SKP111762510531037 Reconstituted Complex
FBXL5SKP111239110531037 Reconstituted Complex
Gene Symbol Interactant Interaction ID References Description
FBXL5SKP118370810531037 Skp1 interacts with Fbl5.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2152883
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-900'