AutismKB 2.0

Annotation Details for KAT2A


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Basic Information Top
Gene Symbol:KAT2A ( GCN5,GCN5L2,MGC102791,PCAF-b,hGCN5 )
Gene Full Name: K(lysine) acetyltransferase 2A
Band: 17q21.2
Quick LinksEntrez ID:2648; OMIM: 602301; Uniprot ID:KAT2A_HUMAN; ENSEMBL ID: ENSG00000108773; HGNC ID: 4201
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000790IEA-nuclear chromatin-
GO:0005615IDA-extracellular space22664934
GO:0005634IDA-nucleus11564863
GO:0005654TAS-nucleoplasm-
GO:0005671IDA-Ada2/Gcn5/Ada3 transcription activator complex18838386
GO:0030914IDA-STAGA complex11564863
GO:0033276IDA-transcription factor TFTC complex10373431
GO:0072686IEA-mitotic spindle-
GO ID Evidence Qualifier GO_term References
GO:0003682IEA-chromatin binding-
GO:0003713IDA-transcription coactivator activity11564863
GO:0004402IDA-histone acetyltransferase activity10373431
GO:0004402IDAcontributes_tohistone acetyltransferase activity11564863
GO:0004402TAS-histone acetyltransferase activity-
GO:0005515IPI-protein binding17664281
GO:0008134IPI-transcription factor binding17301242
GO:0010484IDA-H3 histone acetyltransferase activity18838386
GO:0019903IEA-protein phosphatase binding-
GO:0036459TAS-thiol-dependent ubiquitinyl hydrolase activity-
GO:0042826IPI-histone deacetylase binding12887892
GO:0043997IEA-histone acetyltransferase activity (H4-K12 specific)-
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0001756IEA-somitogenesis-
GO:0001843IEA-neural tube closure-
GO:0006338TAS-chromatin remodeling8552087
GO:0006357TAS-regulation of transcription from RNA polymerase II promoter8552087
GO:0006366TAS-transcription from RNA polymerase II promoter8552087
GO:0008283IEA-cell proliferation-
GO:0014070IEA-response to organic cyclic compound-
GO:0016032IEA-viral process-
GO:0016578IDA-histone deubiquitination18206972
GO:0016579TAS-protein deubiquitination-
GO:0021537IEA-telencephalon development-
GO:0022037IEA-metencephalon development-
GO:0030901IEA-midbrain development-
GO:0031346IEA-positive regulation of cell projection organization-
GO:0031647IMP-regulation of protein stability20562830
GO:0031667IEA-response to nutrient levels-
GO:0035066IEA-positive regulation of histone acetylation-
GO:0035264IEA-multicellular organism growth-
GO:0035948IEA-positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter-
GO:0043966IDA-histone H3 acetylation10373431
GO:0043983IEA-histone H4-K12 acetylation-
GO:0044154IEA-histone H3-K14 acetylation-
GO:0045815TAS-positive regulation of gene expression, epigenetic-
GO:0048312IEA-intracellular distribution of mitochondria-
GO:0055007IEA-cardiac muscle cell differentiation-
GO:0071356IEA-cellular response to tumor necrosis factor-
GO:0071929IEA-alpha-tubulin acetylation-
GO:1903146IMP-regulation of mitophagy24912190
GO:1903955IMP-positive regulation of protein targeting to mitochondrion24912190
GO:1990090IEA-cellular response to nerve growth factor stimulus-
GO:2000679IEA-positive regulation of transcription regulatory region DNA binding-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
KAT2AACTL6A10660111839798 Co-fractionation
KAT2AACTL6A10891811839798 Co-fractionation
KAT2ABRCA110714016260778 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
KAT2ABRCA110891816260778 Affinity Capture-MS; Affinity Capture-Western; Reconstituted Complex
KAT2ACRX10779615932940 Reconstituted Complex
KAT2ACRX10891815932940 Reconstituted Complex
KAT2ACTBP110891816122695 Affinity Capture-Western
KAT2ACTBP110786916122695 Affinity Capture-Western
KAT2ACTNNB110788016510874 Reconstituted Complex
KAT2ACTNNB110891816510874 Reconstituted Complex
KAT2ADDB110891811564863 Affinity Capture-Western; Reconstituted Complex
KAT2ADDB110800911564863 Affinity Capture-Western; Reconstituted Complex
KAT2AE2F110820111418595 Affinity Capture-Western
KAT2AE2F110891811418595 Affinity Capture-Western
KAT2AE2F410820611418595 Affinity Capture-Western
KAT2AE2F410891811418595 Affinity Capture-Western
KAT2AESR110840316260778 Affinity Capture-MS; Affinity Capture-Western
KAT2AESR110891816260778 Affinity Capture-MS; Affinity Capture-Western
KAT2AXRCC61089189488450 Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
KAT2AXRCC61088229488450 Affinity Capture-Western; Co-fractionation; Reconstituted Complex; Two-hybrid
KAT2AGATA210889415001660 Biochemical Activity
KAT2AGATA210891815001660 Biochemical Activity
TADA2AKAT2A1127348972232 9488450 Reconstituted Complex; Two-hybrid
TADA2AKAT2A1089188972232 9488450 Reconstituted Complex; Two-hybrid
XRCC5KAT2A1133539488450 Affinity Capture-Western; Co-fractionation
XRCC5KAT2A1089189488450 Affinity Capture-Western; Co-fractionation
PRKDCKAT2A1115779488450 Biochemical Activity
PRKDCKAT2A1089189488450 Biochemical Activity
IRF1KAT2A10986710022868 Reconstituted Complex
IRF1KAT2A10891810022868 Reconstituted Complex
IRF2KAT2A10986810022868 Reconstituted Complex
IRF2KAT2A10891810022868 Reconstituted Complex
MAXKAT2A10891810611234 Affinity Capture-Western
MAXKAT2A11031910611234 Affinity Capture-Western
MYCKAT2A11069410611234 16287840 17967894 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
MYCKAT2A10891810611234 16287840 17967894 Affinity Capture-Western; Biochemical Activity; Reconstituted Complex
TRRAPKAT2A11390010611234 16260778 16494529 18418385 Affinity Capture-Western; Co-purification
TRRAPKAT2A10891810611234 16260778 16494529 18418385 Affinity Capture-Western; Co-purification
RBPJKAT2A10973610747963 Two-hybrid
RBPJKAT2A10891810747963 Two-hybrid
SUPT3HKAT2A11404211406595 11564863 17967894 Affinity Capture-MS; Affinity Capture-Western
SUPT3HKAT2A10891811406595 11564863 17967894 Affinity Capture-MS; Affinity Capture-Western
TAF4KAT2A11273711406595 Affinity Capture-Western
TAF4KAT2A10891811406595 Affinity Capture-Western
TAF9KAT2A10891811564863 17967894 Affinity Capture-MS; Affinity Capture-Western
TAF9KAT2A11274311564863 17967894 Affinity Capture-MS; Affinity Capture-Western
EID1KAT2A11724311964378 Reconstituted Complex
EID1KAT2A10891811964378 Reconstituted Complex
HSD11B2KAT2A10952412878208 Affinity Capture-Western; Biochemical Activity
HSD11B2KAT2A10891812878208 Affinity Capture-Western; Biochemical Activity
SMAD1KAT2A11026115009097 Affinity Capture-Western
SMAD1KAT2A10891815009097 Affinity Capture-Western
SMAD2KAT2A11026215009097 Affinity Capture-Western
SMAD2KAT2A10891815009097 Affinity Capture-Western
SMAD3KAT2A11026315009097 Affinity Capture-Western
SMAD3KAT2A10891815009097 Affinity Capture-Western
SMAD5KAT2A11026515009097 Affinity Capture-Western
SMAD5KAT2A10891815009097 Affinity Capture-Western
SMAD9KAT2A10891815009097 Affinity Capture-Western
SMAD9KAT2A11026815009097 Affinity Capture-Western
ATXN7KAT2A11222115932940 16494529 17375202 18206972 Affinity Capture-Western
ATXN7KAT2A10891815932940 16494529 17375202 18206972 Affinity Capture-Western
RAD50KAT2A10891816260778 Affinity Capture-Western
RAD50KAT2A11541716260778 Affinity Capture-Western
MSH2KAT2A11057316260778 Affinity Capture-Western
MSH2KAT2A10891816260778 Affinity Capture-Western
HIST1H3AKAT2A11394616287840 Biochemical Activity
HIST1H3AKAT2A10891816287840 Biochemical Activity
HIST1H4AKAT2A11395516287840 Biochemical Activity
HIST1H4AKAT2A10891816287840 Biochemical Activity
TAF10KAT2A11274417375202 17643375 Affinity Capture-MS; Co-purification
TAF10KAT2A10891817375202 17643375 Affinity Capture-MS; Co-purification
MED16KAT2A10891817967894 Affinity Capture-Western
MED16KAT2A11534217967894 Affinity Capture-Western
MED1KAT2A11146517967894 Affinity Capture-Western
MED1KAT2A10891817967894 Affinity Capture-Western
MED17KAT2A11483017967894 Affinity Capture-Western
MED17KAT2A10891817967894 Affinity Capture-Western
SUPT7LKAT2A11524217967894 Affinity Capture-Western
SUPT7LKAT2A10891817967894 Affinity Capture-Western
TADA3KAT2A11573718089809 Affinity Capture-Western
TADA3KAT2A10891818089809 Affinity Capture-Western
USP22KAT2A11691418206972 19615732 Affinity Capture-MS; Affinity Capture-Western
USP22KAT2A10891818206972 19615732 Affinity Capture-MS; Affinity Capture-Western
ENY2KAT2A12126718206972 Affinity Capture-Western
ENY2KAT2A10891818206972 Affinity Capture-Western
ATXN7L3KAT2A12128918206972 Affinity Capture-Western
ATXN7L3KAT2A10891818206972 Affinity Capture-Western
TP53KAT2A10891818250150 Affinity Capture-Western
TP53KAT2A11301018250150 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1343101
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-080403-11'