AutismKB 2.0

Annotation Details for LATS2


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Basic Information Top
Gene Symbol:LATS2 ( FLJ13161,KPM )
Gene Full Name: LATS, large tumor suppressor, homolog 2 (Drosophila)
Band: 13q12.11
Quick LinksEntrez ID:26524; OMIM: 604861; Uniprot ID:LATS2_HUMAN; ENSEMBL ID: ENSG00000150457; HGNC ID: 6515
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0000922IDA-spindle pole12853976
GO:0005634IDA-nucleus10673337
GO:0005634NAS-nucleus10673337
GO:0005815IDA-microtubule organizing center-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity10871863
GO:0004674TAS-protein serine/threonine kinase activity-
GO:0005515IPI-protein binding16413547
GO:0005524IDA-ATP binding10871863
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0000082IDA-G1/S transition of mitotic cell cycle12853976
GO:0001827IEA-inner cell mass cell fate commitment-
GO:0001828IEA-inner cell mass cellular morphogenesis-
GO:0006468IDA-protein phosphorylation10871863
GO:0009755IDA-hormone-mediated signaling pathway15131260
GO:0018105IBA-peptidyl-serine phosphorylation-
GO:0030216IEA-keratinocyte differentiation-
GO:0034613IEA-cellular protein localization-
GO:0035329IDA-hippo signaling20412773
GO:0035329TAS-hippo signaling-
GO:0035556IDA-intracellular signal transduction10871863
GO:0043065IBA-positive regulation of apoptotic process-
GO:0045736IDA-negative regulation of cyclin-dependent protein serine/threonine kinase activity12853976
GO:0046620IBA-regulation of organ growth-
GO:0051301IEA-cell division-
GO:0090090IMP-negative regulation of canonical Wnt signaling pathway20412773
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1354386
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050119-6'