AutismKB 2.0

Annotation Details for GFRA1


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Basic Information Top
Gene Symbol:GFRA1 ( DKFZp313E1012,DKFZp686J0156,FLJ10561,FLJ31546,GDNFR,GDNFRA,GFR-ALPHA-1,MGC23045,RET1L,RETL1,TRNR1 )
Gene Full Name: GDNF family receptor alpha 1
Band: 10q25.3
Quick LinksEntrez ID:2674; OMIM: 601496; Uniprot ID:GFRA1_HUMAN; ENSEMBL ID: ENSG00000151892; HGNC ID: 4243
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0019898TAS-extrinsic component of membrane10829012
GO:0031225IEA-anchored component of membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0005102TAS-receptor binding9545641
GO:0016167TAS-glial cell-derived neurotrophic factor receptor activity10829012
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0007166NAS-cell surface receptor signaling pathway8674117
GO:0007411TAS-axon guidance-
GO:0035860IEA-glial cell-derived neurotrophic factor receptor signaling pathway-
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GFRA1GDNF1089429407096 10829012 Reconstituted Complex
GFRA1GDNF1089369407096 10829012 Reconstituted Complex
RETGFRA11089429192898 10829012 Reconstituted Complex
RETGFRA11119119192898 10829012 Reconstituted Complex
NRTNGFRA11089429407096 10829012 Reconstituted Complex
NRTNGFRA11109589407096 10829012 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GFRA1rs10490904, rs1061413, rs10749189, rs1078080, rs10787627, rs10885877, rs10885886, rs10885888, rs11197557, rs11197567, rs11197612, rs11597916, rs11598215, rs11812459, rs12413585, rs12775655, rs12776813, rs12781658, rs1419877, rs17094340, rs2074986, rs2302105, rs2420245, rs2530340, rs2530341, rs2694773, rs2694783, rs2694798, rs2694801, rs2901100, rs3781504, rs3781514, rs3781518, rs3781523, rs3781532, rs3781539, rs3781543, rs3781550, rs3781553, rs3781556, rs3781557, rs3824840, rs4751956, rs7085306, rs730357, rs7893360, rs7903297, rs7920934, rs881726, rs953920, rs9787429 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1100842
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010226-2'