AutismKB 2.0

Annotation Details for GFRA2


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Basic Information Top
Gene Symbol:GFRA2 ( GDNFRB,NRTNR-ALPHA,NTNRA,RETL2,TRNR2 )
Gene Full Name: GDNF family receptor alpha 2
Band: 8p21.3
Quick LinksEntrez ID:2675; OMIM: 601956; Uniprot ID:GFRA2_HUMAN; ENSEMBL ID: ENSG00000168546; HGNC ID: 4244
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005622IEA-intracellular-
GO:0005886TAS-plasma membrane-
GO:0019898TAS-extrinsic component of membrane10829012
GO:0031225IEA-anchored component of membrane-
GO ID Evidence Qualifier GO_term References
GO:0005088TAS-Ras guanyl-nucleotide exchange factor activity-
GO:0016167IEA-glial cell-derived neurotrophic factor receptor activity-
GO ID Evidence Qualifier GO_term References
GO:0000165TAS-MAPK cascade-
GO:0007169TAS-transmembrane receptor protein tyrosine kinase signaling pathway9192898
GO:0007411TAS-axon guidance-
GO:0031953IEA-negative regulation of protein autophosphorylation-
GO:0033141IEA-positive regulation of peptidyl-serine phosphorylation of STAT protein-
GO:0035860IEA-glial cell-derived neurotrophic factor receptor signaling pathway-
GO:0043547IEA-positive regulation of GTPase activity-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GFRA2GDNF1089439407096 10829012 Reconstituted Complex
GFRA2GDNF1089369407096 10829012 Reconstituted Complex
NRTNGFRA21089439407096 10829012 Reconstituted Complex
NRTNGFRA21109589407096 10829012 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GFRA2rs10088105, rs10283397, rs1128397, rs11993990, rs13250096, rs15881, rs4078157, rs4237073, rs4567027, rs4567028, rs4739217, rs4739285, rs4739286, rs6587002, rs6988470, rs7014143, rs7813735 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:1195462
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040630-1'