AutismKB 2.0

Annotation Details for GH1


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Basic Information Top
Gene Symbol:GH1 ( GH,GH-N,GHN,IGHD1B,hGH-N )
Gene Full Name: growth hormone 1
Band: 17q23.3
Quick LinksEntrez ID:2688; OMIM: 139250; Uniprot ID:SOMA_HUMAN; ENSEMBL ID: ENSG00000189162; HGNC ID: 4261
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space11549663
GO:0031904TAS-endosome lumen-
GO:0070195IDA-growth hormone receptor complex1549776
GO ID Evidence Qualifier GO_term References
GO:0005131IDA-growth hormone receptor binding6303755
GO:0005131IPI-growth hormone receptor binding1549776
GO:0005148IDA-prolactin receptor binding10890569
GO:0005148IPI-prolactin receptor binding7984244
GO:0005179IEA-hormone activity-
GO:0005515IPI-protein binding8943276
GO:0008083IPI-growth factor activity9360546
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0002092IDANOTpositive regulation of receptor internalization9360546
GO:0007259IDA-JAK-STAT cascade8063815
GO:0010536IDA-positive regulation of activation of Janus kinase activity8063815
GO:0014068IDA-positive regulation of phosphatidylinositol 3-kinase signaling7782332
GO:0015758IDA-glucose transport9144201
GO:0032355IDA-response to estradiol12552091
GO:0040018IDA-positive regulation of multicellular organism growth7565946
GO:0040018IMP-positive regulation of multicellular organism growth8496314
GO:0042531IDA-positive regulation of tyrosine phosphorylation of STAT protein8923468
GO:0043406TAS-positive regulation of MAP kinase activity8063815
GO:0043568IDA-positive regulation of insulin-like growth factor receptor signaling pathway7565946
GO:0046427IDA-positive regulation of JAK-STAT cascade8923468
GO:0050731IDA-positive regulation of peptidyl-tyrosine phosphorylation7782332
GO:0060396IDA-growth hormone receptor signaling pathway8063815
GO:0060397TAS-JAK-STAT cascade involved in growth hormone signaling pathway-
GO:0070977IDA-bone maturation20110402
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SHC1GH11089557535773 Biochemical Activity
SHC1GH11123617535773 Biochemical Activity
GHRGH11089557862673 17500058 Reconstituted Complex
GHRGH11089577862673 17500058 Reconstituted Complex
STRAPGH111634217353931 Affinity Capture-MS
STRAPGH110895517353931 Affinity Capture-MS
LTA4HGH110895517353931 Affinity Capture-MS
LTA4HGH111022617353931 Affinity Capture-MS
BTRCGH111445717500058 Reconstituted Complex
BTRCGH110895517500058 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GH1rs2665802 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95707
  • Data Attributes: MGI curated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030725-2'