AutismKB 2.0

Annotation Details for GHRHR


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GHRHR ( GHRFR,GRFR,IGHD1B )
Gene Full Name: growth hormone releasing hormone receptor
Band: 7p14.3
Quick LinksEntrez ID:2692; OMIM: 139191; Uniprot ID:GHRHR_HUMAN; ENSEMBL ID: ENSG00000106128; HGNC ID: 4266
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005637IDA-nuclear inner membrane10461027
GO:0005640IDA-nuclear outer membrane10461027
GO:0005737IDA-cytoplasm10461027
GO:0005886IDA-plasma membrane10461027
GO:0005886TAS-plasma membrane-
GO:0009986IDA-cell surface1333056
GO:0016021IDA-integral component of membrane1333056
GO:0016363IDA-nuclear matrix10461027
GO:0030141IDA-secretory granule10461027
GO:0042383IEA-sarcolemma-
GO ID Evidence Qualifier GO_term References
GO:0004930IC-G-protein coupled receptor activity1333056
GO:0005515IPI-protein binding1333056
GO:0016520IMP-growth hormone-releasing hormone receptor activity7680413
GO:0017046IPI-peptide hormone binding7680413
GO:0019838IPI-growth factor binding7680413
GO ID Evidence Qualifier GO_term References
GO:0007166IEA-cell surface receptor signaling pathway-
GO:0007189IDA-adenylate cyclase-activating G-protein coupled receptor signaling pathway1333056
GO:0007190IEA-activation of adenylate cyclase activity-
GO:0007595IEA-lactation-
GO:0008284IDA-positive regulation of cell proliferation12867592
GO:0008340IEA-determination of adult lifespan-
GO:0019933IMP-cAMP-mediated signaling7680413
GO:0030104IEA-water homeostasis-
GO:0030252IEA-growth hormone secretion-
GO:0030819IDA-positive regulation of cAMP biosynthetic process1333056
GO:0032868IMP-response to insulin17356054
GO:0032869IEA-cellular response to insulin stimulus-
GO:0033143IEA-regulation of intracellular steroid hormone receptor signaling pathway-
GO:0040018IMP-positive regulation of multicellular organism growth8528260
GO:0042445IEA-hormone metabolic process-
GO:0043568NAS-positive regulation of insulin-like growth factor receptor signaling pathway11773624
GO:0043627IDA-response to estrogen9482665
GO:0046010IEA-positive regulation of circadian sleep/wake cycle, non-REM sleep-
GO:0048469IEA-cell maturation-
GO:0048609NAS-multicellular organismal reproductive process15944917
GO:0051246IEA-regulation of protein metabolic process-
GO:0051384IDA-response to glucocorticoid9482665
GO:0060124NAS-positive regulation of growth hormone secretion11773624
GO:0060133IEA-somatotropin secreting cell development-
GO:0071333IEA-cellular response to glucose stimulus-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95710
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050315-2'