AutismKB 2.0

Annotation Details for PABPC1


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Basic Information Top
Gene Symbol:PABPC1 ( PAB1,PABP,PABP1,PABPC2,PABPL1 )
Gene Full Name: poly(A) binding protein, cytoplasmic 1
Band: 8q22.3
Quick LinksEntrez ID:26986; OMIM: 604679; Uniprot ID:PABP1_HUMAN; ENSEMBL ID: ENSG00000070756; HGNC ID: 8554
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus21940797
GO:0005737TAS-cytoplasm9582337
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0005925IDA-focal adhesion21423176
GO:0010494IDA-cytoplasmic stress granule21883093
GO:0016020IDA-membrane19946888
GO:0030425IEA-dendrite-
GO:0030529IDA-intracellular ribonucleoprotein complex17289661
GO:0036464IDA-cytoplasmic ribonucleoprotein granule15121898
GO:0070062IDA-extracellular exosome23533145
GO:0071013IDA-catalytic step 2 spliceosome11991638
GO:1990124IEA-messenger ribonucleoprotein complex-
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22658674
GO:0003730IDA-mRNA 3'-UTR binding16126846
GO:0005515IPI-protein binding11051545
GO:0008022IPI-protein C-terminus binding15663938
GO:0008143IDA-poly(A) binding16804161
GO:0008143TAS-poly(A) binding2885805
GO:0008266IDA-poly(U) RNA binding21984414
GO:0008494TAS-translation activator activity11997512
GO ID Evidence Qualifier GO_term References
GO:0000184TAS-nuclear-transcribed mRNA catabolic process, nonsense-mediated decay-
GO:0000289TAS-nuclear-transcribed mRNA poly(A) tail shortening-
GO:0000398IC-mRNA splicing, via spliceosome11991638
GO:0006378TAS-mRNA polyadenylation2885805
GO:0006413TAS-translational initiation-
GO:0031047ISS-gene silencing by RNA-
GO:0043488TAS-regulation of mRNA stability-
GO:0045070IMP-positive regulation of viral genome replication26735137
GO:0045727IEA-positive regulation of translation-
GO:0048255TAS-mRNA stabilization11997512
GO:0060213ISS-positive regulation of nuclear-transcribed mRNA poly(A) tail shortening-
GO:1900153ISS-positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay-
GO:2000623IDA-negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay18447585
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PABPC1APBB111793916055720 Affinity Capture-MS
PABPC1APBB110681916055720 Affinity Capture-MS
PABPC1AIRE10682320085707 Affinity Capture-MS
PABPC1AIRE11793920085707 Affinity Capture-MS
PABPC1EIF4A11179399548260 Affinity Capture-Western
PABPC1EIF4A11082899548260 Affinity Capture-Western
PABPC1EIF4A211793917353931 Affinity Capture-MS
PABPC1EIF4A210829017353931 Affinity Capture-MS
PABPC1EIF4B11793911274152 Reconstituted Complex
PABPC1EIF4B10829111274152 Reconstituted Complex
PABPC1EIF4G11082969857202 Affinity Capture-Western; Reconstituted Complex
PABPC1EIF4G11179399857202 Affinity Capture-Western; Reconstituted Complex
PABPC1ETF111793918056425 Affinity Capture-Western
PABPC1ETF110840818056425 Affinity Capture-Western
PABPC1GSPT110919010358005 Reconstituted Complex
PABPC1GSPT111793910358005 Reconstituted Complex
PABPC1H2AFX11793916522924 Affinity Capture-MS
PABPC1H2AFX10926816522924 Affinity Capture-MS
PABPC1HNRNPA110942017643375 Affinity Capture-MS
PABPC1HNRNPA111793917643375 Affinity Capture-MS
PABPC1PIN111793916055720 Affinity Capture-MS
PABPC1PIN111131716055720 Affinity Capture-MS
PABPC1PXN11178711704675 Affinity Capture-Western
PABPC1PXN11793911704675 Affinity Capture-Western
PABPC1UPF111793912723973 Affinity Capture-MS
PABPC1UPF111190812723973 Affinity Capture-MS
PABPC1BCAR311793917353931 Affinity Capture-MS
PABPC1BCAR311400017353931 Affinity Capture-MS
PABPC1DYNLL111420617353931 Affinity Capture-MS
PABPC1DYNLL111793917353931 Affinity Capture-MS
PABPC1EIF4G31179399857202 Affinity Capture-Western
PABPC1EIF4G31142209857202 Affinity Capture-Western
PABPC1IKBKE11793917353931 Affinity Capture-MS
PABPC1IKBKE11500017353931 Affinity Capture-MS
PABPC1PAN211525214583602 Affinity Capture-Western
PABPC1PAN211793914583602 Affinity Capture-Western
PABPC1TOB111793918056425 Affinity Capture-Western
PABPC1TOB111544318056425 Affinity Capture-Western
PABPC1GNB2L111793912388589 Affinity Capture-MS
PABPC1GNB2L111567112388589 Affinity Capture-MS
PABPC1PAIP11158519548260 11997512 Affinity Capture-Western; Far Western; Reconstituted Complex
PABPC1PAIP11179399548260 11997512 Affinity Capture-Western; Far Western; Reconstituted Complex
PABPC1WBP411636316055720 Affinity Capture-MS
PABPC1WBP411793916055720 Affinity Capture-MS
PABPC1PUF6011793917353931 Affinity Capture-MS
PABPC1PUF6011650217353931 Affinity Capture-MS
PABPC1GSPT211793910358005 Reconstituted Complex; Two-hybrid
PABPC1GSPT211722110358005 Reconstituted Complex; Two-hybrid
PABPC1GIGYF211793920696395 Affinity Capture-MS
PABPC1GIGYF211752020696395 Affinity Capture-MS
PAIP2PABPC111793911438674 Far Western; Reconstituted Complex
PAIP2PABPC111940411438674 Far Western; Reconstituted Complex
ANAPC5PABPC111953715082755 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
ANAPC5PABPC111793915082755 Affinity Capture-Western; Reconstituted Complex; Two-hybrid
WWOXPABPC111793916055720 Affinity Capture-MS
WWOXPABPC111970716055720 Affinity Capture-MS
ITCHPABPC111793916055720 Affinity Capture-MS
ITCHPABPC112374716055720 Affinity Capture-MS
PRMT6PABPC111793916293633 Biochemical Activity
PRMT6PABPC112046916293633 Biochemical Activity
PINX1PABPC111793917353931 Affinity Capture-MS
PINX1PABPC112031917353931 Affinity Capture-MS
PAN3PABPC111793918056425 Affinity Capture-Western; Reconstituted Complex
PAN3PABPC112912918056425 Affinity Capture-Western; Reconstituted Complex
CNOT7PABPC111893818056425 Affinity Capture-Western; Reconstituted Complex
CNOT7PABPC111793918056425 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1349722
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-3238'