AutismKB 2.0

Annotation Details for NPTN


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Basic Information Top
Gene Symbol:NPTN ( DKFZp686L2477,GP55,GP65,MGC102805,SDFR1,SDR1,np55,np65 )
Gene Full Name: neuroplastin
Band: 15q24.1
Quick LinksEntrez ID:27020; OMIM: 612820; Uniprot ID:NPTN_HUMAN; ENSEMBL ID: ENSG00000156642; HGNC ID: 17867
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0009986IDA-cell surface19581412
GO:0014069IEA-postsynaptic density-
GO:0016021IEA-integral component of membrane-
GO:0030425IEA-dendrite-
GO:0042734ISS-presynaptic membrane-
GO:0060077IEA-inhibitory synapse-
GO ID Evidence Qualifier GO_term References
GO:0005105ISS-type 1 fibroblast growth factor receptor binding-
GO:0044325IEA-ion channel binding-
GO:0050839ISS-cell adhesion molecule binding-
GO ID Evidence Qualifier GO_term References
GO:0001934ISS-positive regulation of protein phosphorylation-
GO:0007156ISS-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007204ISS-positive regulation of cytosolic calcium ion concentration-
GO:0008542IEA-visual learning-
GO:0010976ISS-positive regulation of neuron projection development-
GO:0045743ISS-positive regulation of fibroblast growth factor receptor signaling pathway-
GO:0048170ISS-positive regulation of long-term neuronal synaptic plasticity-
GO:0060291ISS-long-term synaptic potentiation-
GO:0070374IEA-positive regulation of ERK1 and ERK2 cascade-
GO:1900273IEA-positive regulation of long-term synaptic potentiation-
GO:1902683IEA-regulation of receptor localization to synapse-
GO:1903829IEA-positive regulation of cellular protein localization-
GO:1904861IEA-excitatory synapse assembly-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NPTNrs3743500, rs3826047, rs3840846 Gene overview in SZGene
Animal Model Top
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030804-7'