AutismKB 2.0

Annotation Details for NPTN


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Basic Information Top
Gene Symbol:NPTN ( DKFZp686L2477,GP55,GP65,MGC102805,SDFR1,SDR1,np55,np65 )
Gene Full Name: neuroplastin
Band: 15q24.1
Quick LinksEntrez ID:27020; OMIM: 612820; Uniprot ID:NPTN_HUMAN; ENSEMBL ID: ENSG00000156642; HGNC ID: 17867
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0009986IDA-cell surface19581412
GO:0014069IEA-postsynaptic density-
GO:0016021IEA-integral component of membrane-
GO:0030425IEA-dendrite-
GO:0042734ISS-presynaptic membrane-
GO:0060077IEA-inhibitory synapse-
GO ID Evidence Qualifier GO_term References
GO:0005105ISS-type 1 fibroblast growth factor receptor binding-
GO:0044325IEA-ion channel binding-
GO:0050839ISS-cell adhesion molecule binding-
GO ID Evidence Qualifier GO_term References
GO:0001934ISS-positive regulation of protein phosphorylation-
GO:0007156ISS-homophilic cell adhesion via plasma membrane adhesion molecules-
GO:0007204ISS-positive regulation of cytosolic calcium ion concentration-
GO:0008542IEA-visual learning-
GO:0010976ISS-positive regulation of neuron projection development-
GO:0045743ISS-positive regulation of fibroblast growth factor receptor signaling pathway-
GO:0048170ISS-positive regulation of long-term neuronal synaptic plasticity-
GO:0060291ISS-long-term synaptic potentiation-
GO:0070374IEA-positive regulation of ERK1 and ERK2 cascade-
GO:1900273IEA-positive regulation of long-term synaptic potentiation-
GO:1902683IEA-regulation of receptor localization to synapse-
GO:1903829IEA-positive regulation of cellular protein localization-
GO:1904861IEA-excitatory synapse assembly-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
NPTNrs3743500, rs3826047, rs3840846 Gene overview in SZGene
Animal Model Top