AutismKB 2.0

Annotation Details for GPC3


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Basic Information Top
Gene Symbol:GPC3 ( DGSX,GTR2-2,MXR7,OCI-5,SDYS,SGB,SGBS,SGBS1 )
Gene Full Name: glypican 3
Band: Xq26.2
Quick LinksEntrez ID:2719; OMIM: 300037; Uniprot ID:GPC3_HUMAN; ENSEMBL ID: ENSG00000147257; HGNC ID: 4451
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005578IEA-proteinaceous extracellular matrix-
GO:0005615IEA-extracellular space-
GO:0005788TAS-endoplasmic reticulum lumen-
GO:0005796TAS-Golgi lumen-
GO:0005886TAS-plasma membrane-
GO:0005887TAS-integral component of plasma membrane7657705
GO:0043202TAS-lysosomal lumen-
GO:0046658IEA-anchored component of plasma membrane-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding17549790
GO:0043395IEA-heparan sulfate proteoglycan binding-
GO:0060422IDA-peptidyl-dipeptidase inhibitor activity17549790
GO ID Evidence Qualifier GO_term References
GO:0001523TAS-retinoid metabolic process-
GO:0001658IEA-branching involved in ureteric bud morphogenesis-
GO:0006024TAS-glycosaminoglycan biosynthetic process-
GO:0006027TAS-glycosaminoglycan catabolic process-
GO:0009653TAS-anatomical structure morphogenesis8589713
GO:0009948IEA-anterior/posterior axis specification-
GO:0010171IEA-body morphogenesis-
GO:0010466IEA-negative regulation of peptidase activity-
GO:0030203TAS-glycosaminoglycan metabolic process-
GO:0030282IEA-bone mineralization-
GO:0030316IEA-osteoclast differentiation-
GO:0030324IEA-lung development-
GO:0030513IEA-positive regulation of BMP signaling pathway-
GO:0035116IEA-embryonic hindlimb morphogenesis-
GO:0043687TAS-post-translational protein modification-
GO:0044267TAS-cellular protein metabolic process-
GO:0045732IEA-positive regulation of protein catabolic process-
GO:0045807IEA-positive regulation of endocytosis-
GO:0045879IEA-negative regulation of smoothened signaling pathway-
GO:0045880IEA-positive regulation of smoothened signaling pathway-
GO:0045926IEA-negative regulation of growth-
GO:0046326IEA-positive regulation of glucose import-
GO:0050680IEA-negative regulation of epithelial cell proliferation-
GO:0060976IEA-coronary vasculature development-
GO:0072138ISS-mesenchymal cell proliferation involved in ureteric bud development-
GO:0072180IEA-mesonephric duct morphogenesis-
GO:0072203IEA-cell proliferation involved in metanephros development-
GO:0090090IEA-negative regulation of canonical Wnt signaling pathway-
GO:2000096IEA-positive regulation of Wnt signaling pathway, planar cell polarity pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GPC3FGF210853812478660 Affinity Capture-Western
GPC3FGF210898312478660 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:104903
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-031212-1'