AutismKB 2.0

Annotation Details for TNFRSF21


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Basic Information Top
Gene Symbol:TNFRSF21 ( BM-018,DR6,MGC31965 )
Gene Full Name: tumor necrosis factor receptor superfamily, member 21
Band: 6p12.3
Quick LinksEntrez ID:27242; OMIM: 605732; Uniprot ID:TNR21_HUMAN; ENSEMBL ID: ENSG00000146072; HGNC ID: 13469
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane19654028
GO:0030424IEA-axon-
GO:0031226ISS-intrinsic component of plasma membrane-
GO ID Evidence Qualifier GO_term References
GO:0005031IBA-tumor necrosis factor-activated receptor activity-
GO:0005515IPI-protein binding19225519
GO ID Evidence Qualifier GO_term References
GO:0001783ISS-B cell apoptotic process-
GO:0002250ISS-adaptive immune response-
GO:0006915IMP-apoptotic process22761420
GO:0006954IBA-inflammatory response-
GO:0006955IBA-immune response-
GO:0006959ISS-humoral immune response-
GO:0019216TAS-regulation of lipid metabolic process-
GO:0030889ISS-negative regulation of B cell proliferation-
GO:0031642IMP-negative regulation of myelination21725297
GO:0032496IBA-response to lipopolysaccharide-
GO:0033209IEA-tumor necrosis factor-mediated signaling pathway-
GO:0042127IBA-regulation of cell proliferation-
GO:0042130ISS-negative regulation of T cell proliferation-
GO:0042552ISS-myelination-
GO:0042981IBA-regulation of apoptotic process-
GO:0048713IBA-regulation of oligodendrocyte differentiation-
GO:0048713ISS-regulation of oligodendrocyte differentiation-
GO:0050852ISS-T cell receptor signaling pathway-
GO:0051402ISS-neuron apoptotic process-
GO:0071356IDA-cellular response to tumor necrosis factor19654028
GO:0097190IBA-apoptotic signaling pathway-
GO:0097252ISS-oligodendrocyte apoptotic process-
GO:2000663ISS-negative regulation of interleukin-5 secretion-
GO:2000666ISS-negative regulation of interleukin-13 secretion-
GO:2001180ISS-negative regulation of interleukin-10 secretion-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TNFRSF21TRADD1142579714541 Affinity Capture-Western
TNFRSF21TRADD1180909714541 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2151075
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-5971'