AutismKB 2.0

Annotation Details for SESN1


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Basic Information Top
Gene Symbol:SESN1 ( MGC138241,MGC142129,PA26,RP11-787I22.1,SEST1 )
Gene Full Name: sestrin 1
Band: 6q21
Quick LinksEntrez ID:27244; OMIM: 606103; Uniprot ID:SESN1_HUMAN; ENSEMBL ID: ENSG00000080546; HGNC ID: 21595
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0001650IDA-fibrillar center-
GO:0005634IDA-nucleus9926927
GO:0005737IDA-cytoplasm15105503
GO:0005829TAS-cytosol-
GO:0061700IDAcolocalizes_withGATOR2 complex25263562
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding15105503
GO:0051920IEA-peroxiredoxin activity-
GO:0070728IDA-leucine binding26449471
GO ID Evidence Qualifier GO_term References
GO:0034198IMP-cellular response to amino acid starvation25263562
GO:0042149IMP-cellular response to glucose starvation25263562
GO:0055114IEA-oxidation-reduction process-
GO:0072593IMP-reactive oxygen species metabolic process15105503
GO:0098869IMP-cellular oxidant detoxification15105503
GO:1901031IEA-regulation of response to reactive oxygen species-
GO:1904262IMP-negative regulation of TORC1 signaling18692468
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SESN1PRDX111809215105503 Affinity Capture-Western
SESN1PRDX111108915105503 Affinity Capture-Western
Gene Symbol Interactant Interaction ID References Description
SESN1PRDX113061015105503 PrxI interacts with PA26.
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:2155278
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-040718-408'