AutismKB 2.0

Annotation Details for PDCD4


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Basic Information Top
Gene Symbol:PDCD4 ( H731,MGC33046,MGC33047 )
Gene Full Name: programmed cell death 4 (neoplastic transformation inhibitor)
Band: 10q25.2
Quick LinksEntrez ID:27250; OMIM: 608610; Uniprot ID:PDCD4_HUMAN; ENSEMBL ID: ENSG00000150593; HGNC ID: 8763
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IMP-nucleus16357133
GO:0005634ISS-nucleus-
GO:0005737IMP-cytoplasm16357133
GO:0005829IDA-cytosol12054647
GO ID Evidence Qualifier GO_term References
GO:0003723IEA-RNA binding-
GO:0005515IPI-protein binding12054647
GO ID Evidence Qualifier GO_term References
GO:0006915NAS-apoptotic process12054647
GO:0007569IDA-cell aging12054647
GO:0030509IDA-BMP signaling pathway18548003
GO:0034393IEA-positive regulation of smooth muscle cell apoptotic process-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0043508ISS-negative regulation of JUN kinase activity-
GO:0045786NAS-negative regulation of cell cycle12054647
GO:0045892IDA-negative regulation of transcription, DNA-templated16357133
GO:0045892ISS-negative regulation of transcription, DNA-templated-
GO:0050729ISS-positive regulation of inflammatory response-
GO:0060940ISS-epithelial to mesenchymal transition involved in cardiac fibroblast development-
GO:0071222ISS-cellular response to lipopolysaccharide-
GO:1900016ISS-negative regulation of cytokine production involved in inflammatory response-
GO:1901224IMP-positive regulation of NIK/NF-kappaB signaling19946272
GO:1904761IMP-negative regulation of myofibroblast differentiation20533548
GO:1905064IDA-negative regulation of vascular smooth muscle cell differentiation18548003
GO:2000353IMP-positive regulation of endothelial cell apoptotic process24732886
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
PDCD4EIF4A111809817353931 Affinity Capture-MS
PDCD4EIF4A110828917353931 Affinity Capture-MS
PDCD4EIF4A211809817353931 Affinity Capture-MS
PDCD4EIF4A210829017353931 Affinity Capture-MS
PDCD4EIF4G110829612054647 Affinity Capture-Western
PDCD4EIF4G111809812054647 Affinity Capture-Western
PDCD4EMD11809817620012 Affinity Capture-MS
PDCD4EMD10832517620012 Affinity Capture-MS
PDCD4RPL511204512054647 Reconstituted Complex; Two-hybrid
PDCD4RPL511809812054647 Reconstituted Complex; Two-hybrid
PDCD4RPS1311809812054647 Reconstituted Complex; Two-hybrid
PDCD4RPS1311212112054647 Reconstituted Complex; Two-hybrid
PDCD4UBC11316418296647 Affinity Capture-Western
PDCD4UBC11809818296647 Affinity Capture-Western
PDCD4BTRC11809818296647 Affinity Capture-Western
PDCD4BTRC11445718296647 Affinity Capture-Western
PDCD4FBXW1111688719615732 Affinity Capture-MS
PDCD4FBXW1111809819615732 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:107490
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-9847'