AutismKB 2.0

Annotation Details for STK39


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Basic Information Top
Gene Symbol:STK39 ( DCHT,DKFZp686K05124,PASK,SPAK )
Gene Full Name: serine threonine kinase 39
Band: 2q24.3
Quick LinksEntrez ID:27347; OMIM: 607648; Uniprot ID:STK39_HUMAN; ENSEMBL ID: ENSG00000198648; HGNC ID: 17717
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634NAS-nucleus10980603
GO:0005654IDA-nucleoplasm-
GO:0005737IBA-cytoplasm-
GO:0005737NAS-cytoplasm10980603
GO:0005829IDA-cytosol-
GO:0005829ISS-cytosol-
GO:0005856IEA-cytoskeleton-
GO:0016323IEA-basolateral plasma membrane-
GO:0016324IEA-apical plasma membrane-
GO:0019898ISS-extrinsic component of membrane-
GO:0043231IDA-intracellular membrane-bounded organelle-
GO ID Evidence Qualifier GO_term References
GO:0004674IDA-protein serine/threonine kinase activity24393035
GO:0004674IMP-protein serine/threonine kinase activity16669787
GO:0004702IBA-signal transducer, downstream of receptor, with serine/threonine kinase activity-
GO:0004702NAS-signal transducer, downstream of receptor, with serine/threonine kinase activity10980603
GO:0005515IPI-protein binding16669787
GO:0005524IEA-ATP binding-
GO:0016301ISS-kinase activity-
GO:0019901IEA-protein kinase binding-
GO ID Evidence Qualifier GO_term References
GO:0001933IEA-negative regulation of protein phosphorylation-
GO:0006468ISS-protein phosphorylation-
GO:0006468NAS-protein phosphorylation10980603
GO:0006950NAS-response to stress10980603
GO:0008217IEA-regulation of blood pressure-
GO:0018105IDA-peptidyl-serine phosphorylation24393035
GO:0018107IDA-peptidyl-threonine phosphorylation24393035
GO:0018107IMP-peptidyl-threonine phosphorylation16669787
GO:0023014IDA-signal transduction by protein phosphorylation24393035
GO:0023016IMP-signal transduction by trans-phosphorylation16669787
GO:0032414ISS-positive regulation of ion transmembrane transporter activity-
GO:0035556IDA-intracellular signal transduction24393035
GO:0036438ISS-maintenance of lens transparency-
GO:0043268IEA-positive regulation of potassium ion transport-
GO:0046777ISS-protein autophosphorylation-
GO:0050727IEA-regulation of inflammatory response-
GO:0071476IC-cellular hypotonic response24393035
GO:0090188IEA-negative regulation of pancreatic juice secretion-
GO:1901017IDA-negative regulation of potassium ion transmembrane transporter activity24393035
GO:1901380IDA-negative regulation of potassium ion transmembrane transport24393035
GO:1905408IDA-negative regulation of creatine transmembrane transporter activity25531585
GO:2000021IEA-regulation of ion homeostasis-
GO:2000650IDA-negative regulation of sodium ion transmembrane transporter activity25531585
GO:2000681IDA-negative regulation of rubidium ion transport24393035
GO:2000687IDA-negative regulation of rubidium ion transmembrane transporter activity24393035
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
STK39MAPK1411815914563843 Affinity Capture-Western
STK39MAPK1410781914563843 Affinity Capture-Western
STK39GSN10918914563843 Two-hybrid
STK39GSN11815914563843 Two-hybrid
STK39MBP11032510980603 Biochemical Activity
STK39MBP11815910980603 Biochemical Activity
STK39SLC12A211244714563843 Two-hybrid
STK39SLC12A211815914563843 Two-hybrid
STK39OTOF11815914563843 Two-hybrid
STK39OTOF11478214563843 Two-hybrid
STK39AATK11498414563843 Two-hybrid
STK39AATK11815914563843 Two-hybrid
STK39HSPH111602214563843 Two-hybrid
STK39HSPH111815914563843 Two-hybrid
STK39STK3911815910980603 Biochemical Activity
WNK4STK3911815914563843 Two-hybrid
WNK4STK3912242114563843 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1858416
  • Data Attributes: MGI curated and HomoloGene calculated
No data