AutismKB 2.0

Annotation Details for GLI1


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GLI1 ( GLI )
Gene Full Name: GLI family zinc finger 1
Band: 12q13.3
Quick LinksEntrez ID:2735; OMIM: 165220; Uniprot ID:GLI1_HUMAN; ENSEMBL ID: ENSG00000111087; HGNC ID: 4317
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005634IDA-nucleus10806483
GO:0005654IDA-nucleoplasm-
GO:0005654TAS-nucleoplasm-
GO:0005737IDA-cytoplasm10504446
GO:0005829IDA-cytosol18559511
GO:0005829TAS-cytosol-
GO:0005930IEA-axoneme-
GO:0097542TAS-ciliary tip-
GO:0097546TAS-ciliary base-
GO ID Evidence Qualifier GO_term References
GO:0000977IDA-RNA polymerase II regulatory region sequence-specific DNA binding18298960
GO:0000978IEA-RNA polymerase II core promoter proximal region sequence-specific DNA binding-
GO:0003677IDA-DNA binding9118802
GO:0003682IEA-chromatin binding-
GO:0003705IEA-transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding-
GO:0005515IPI-protein binding10564661
GO:0008017IEA-microtubule binding-
GO:0044212IDA-transcription regulatory region DNA binding17035233
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001649IDA-osteoblast differentiation12165851
GO:0006351IEA-transcription, DNA-templated-
GO:0007224IDA-smoothened signaling pathway19878745
GO:0007224TAS-smoothened signaling pathway11001584
GO:0007283IEA-spermatogenesis-
GO:0007418IEA-ventral midline development-
GO:0008284IMP-positive regulation of cell proliferation12165851
GO:0008589TAS-regulation of smoothened signaling pathway11238441
GO:0009611IEA-response to wounding-
GO:0009913IDA-epidermal cell differentiation12165851
GO:0009953IEA-dorsal/ventral pattern formation-
GO:0009954IEA-proximal/distal pattern formation-
GO:0021696IEA-cerebellar cortex morphogenesis-
GO:0021938IEA-smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation-
GO:0021983IEA-pituitary gland development-
GO:0030324IEA-lung development-
GO:0045667IEA-regulation of osteoblast differentiation-
GO:0045740IDA-positive regulation of DNA replication12165851
GO:0045880IDA-positive regulation of smoothened signaling pathway17035233
GO:0045893IDA-positive regulation of transcription, DNA-templated11238441
GO:0045944IDA-positive regulation of transcription from RNA polymerase II promoter9118802
GO:0048546TAS-digestive tract morphogenesis11001584
GO:0060032IEA-notochord regression-
GO:0060070IEA-canonical Wnt signaling pathway-
GO:0090090IMP-negative regulation of canonical Wnt signaling pathway17035233
GO:0097421IEA-liver regeneration-
GO:2000345IEA-regulation of hepatocyte proliferation-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SUFUGLI111967610559945 10564661 12426310 Affinity Capture-Western; Far Western; Reconstituted Complex
SUFUGLI110899710559945 10564661 12426310 Affinity Capture-Western; Far Western; Reconstituted Complex
STK36GLI111803210806483 Affinity Capture-Western; Co-localization
STK36GLI110899710806483 Affinity Capture-Western; Co-localization
ZIC2GLI111337811238441 Affinity Capture-Western
ZIC2GLI110899711238441 Affinity Capture-Western
ZIC1GLI111337711238441 Affinity Capture-Western; Reconstituted Complex
ZIC1GLI110899711238441 Affinity Capture-Western; Reconstituted Complex
SAP18GLI111557311960000 Affinity Capture-Western; Phenotypic Suppression
SAP18GLI110899711960000 Affinity Capture-Western; Phenotypic Suppression
HDAC1GLI110931520081843 Affinity Capture-Western
HDAC1GLI110899720081843 Affinity Capture-Western
HDAC2GLI110931620081843 Affinity Capture-Western
HDAC2GLI110899720081843 Affinity Capture-Western
RAI1GLI111596620211142 Two-hybrid
RAI1GLI110899720211142 Two-hybrid
XBP1GLI111333120211142 Two-hybrid
XBP1GLI110899720211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95727
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030321-1'