AutismKB 2.0

Annotation Details for BIN1


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Basic Information Top
Gene Symbol:BIN1 ( AMPH2,AMPHL,DKFZp547F068,MGC10367,SH3P9 )
Gene Full Name: bridging integrator 1
Band: 2q14.3
Quick LinksEntrez ID:274; OMIM: 601248; Uniprot ID:BIN1_HUMAN; ENSEMBL ID: ENSG00000136717; HGNC ID: 1052
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005635IEA-nuclear envelope-
GO:0005737IDA-cytoplasm-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0015629TAS-actin cytoskeleton9182667
GO:0016020IDA-membrane16530520
GO:0030018ISS-Z disc-
GO:0030315ISS-T-tubule-
GO:0030424IDA-axon23399914
GO:0031674ISS-I band-
GO:0033268ISS-node of Ranvier-
GO:0043194ISS-axon initial segment-
GO:0060987IMP-lipid tube19004523
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding10903846
GO:0042802IPI-identical protein binding23917616
GO:0048156IPI-tau protein binding23399914
GO:0051015IDA-actin filament binding26506308
GO:0070063IPI-RNA polymerase binding16530520
GO ID Evidence Qualifier GO_term References
GO:0006897IEA-endocytosis-
GO:0006997IMP-nucleus organization26506308
GO:0008283TAS-cell proliferation8782822
GO:0016032IEA-viral process-
GO:0030100IEA-regulation of endocytosis-
GO:0042692IEA-muscle cell differentiation-
GO:0043065IDA-positive regulation of apoptotic process16530520
GO:0043065IMP-positive regulation of apoptotic process10412034
GO:0045664IMP-regulation of neuron differentiation10412034
GO:0048711IMP-positive regulation of astrocyte differentiation10412034
GO:0051647IEA-nucleus localization-
GO:0060988IMP-lipid tube assembly19004523
GO:0061024TAS-membrane organization-
GO:0071156IDA-regulation of cell cycle arrest10412034
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
BIN1AMPH1067709348539 Affinity Capture-Western
BIN1AMPH1067719348539 Affinity Capture-Western
ITGA6BIN110986410094488 Two-hybrid
ITGA6BIN110677110094488 Two-hybrid
ITGA1BIN110677110094488 Two-hybrid
ITGA1BIN110987910094488 Two-hybrid
ITGA3BIN110677110094488 Two-hybrid
ITGA3BIN110988210094488 Two-hybrid
MYCBIN111069410380878 Reconstituted Complex
MYCBIN110677110380878 Reconstituted Complex
BIN1BIN110677110391921 Reconstituted Complex
PLD1BIN111135310764771 Phenotypic Suppression; Reconstituted Complex
PLD1BIN110677110764771 Phenotypic Suppression; Reconstituted Complex
PLD2BIN111135410764771 Phenotypic Suppression; Reconstituted Complex
PLD2BIN110677110764771 Phenotypic Suppression; Reconstituted Complex
SYN1BIN111271910899172 Affinity Capture-Western
SYN1BIN110677110899172 Affinity Capture-Western
SH3GLB1BIN111928912456676 Reconstituted Complex
SH3GLB1BIN110677112456676 Reconstituted Complex
SH3GL2BIN111235312456676 Reconstituted Complex
SH3GL2BIN110677112456676 Reconstituted Complex
PTK2BIN110677112558988 Affinity Capture-Western
PTK2BIN111171912558988 Affinity Capture-Western
SNX4BIN111426212668730 Affinity Capture-Western; Two-hybrid
SNX4BIN110677112668730 Affinity Capture-Western; Two-hybrid
RIN3BIN112297412972505 Affinity Capture-Western; Reconstituted Complex
RIN3BIN110677112972505 Affinity Capture-Western; Reconstituted Complex
CUX1BIN110790316169070 Two-hybrid
CUX1BIN110677116169070 Two-hybrid
XRCC6BIN110677117671430 Co-purification
XRCC6BIN110882217671430 Co-purification
XRCC5BIN111335317671430 Co-purification
XRCC5BIN110677117671430 Co-purification
RFX3BIN111192320211142 Two-hybrid
RFX3BIN110677120211142 Two-hybrid
ZBTB3BIN112293320211142 Two-hybrid
ZBTB3BIN110677120211142 Two-hybrid
No data
No data
AlzGene, PDGene and SZGene Top
Gene Symbol Poly Names Gene overview in AlzGene
BIN1rs744373, rs7561528 Gene overview in AlzGene
No data
No data
Animal Model Top
  • MGI ID: MGI:108092
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030425-1'