AutismKB 2.0

Annotation Details for GNA12


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Basic Information Top
Gene Symbol:GNA12 ( MGC104623,MGC99644,NNX3,RMP,gep )
Gene Full Name: guanine nucleotide binding protein (G protein) alpha 12
Band: 7p22.3-p22.2
Quick LinksEntrez ID:2768; OMIM: 604394; Uniprot ID:GNA12_HUMAN; ENSEMBL ID: ENSG00000146535; HGNC ID: 4380
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005737IEA-cytoplasm-
GO:0005834IBA-heterotrimeric G-protein complex-
GO:0005886TAS-plasma membrane-
GO:0005925IDA-focal adhesion21423176
GO:0016328IEA-lateral plasma membrane-
GO:0031526IBA-brush border membrane-
GO ID Evidence Qualifier GO_term References
GO:0003924IBA-GTPase activity-
GO:0003924TAS-GTPase activity-
GO:0004871IBA-signal transducer activity-
GO:0005515IPI-protein binding10026210
GO:0005525IEA-GTP binding-
GO:0031683IBA-G-protein beta/gamma-subunit complex binding-
GO:0031752IBA-D5 dopamine receptor binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001701IEA-in utero embryonic development-
GO:0007186TAS-G-protein coupled receptor signaling pathway8290554
GO:0007188IBA-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-
GO:0007266IBA-Rho protein signal transduction-
GO:0007596TAS-blood coagulation8290554
GO:0008360IEA-regulation of cell shape-
GO:0010762ISS-regulation of fibroblast migration-
GO:0030154IEA-cell differentiation-
GO:0030168TAS-platelet activation-
GO:0032006IMP-regulation of TOR signaling22609986
GO:0032434IMP-regulation of proteasomal ubiquitin-dependent protein catabolic process22609986
GO:0042493IEA-response to drug-
GO:0042733IEA-embryonic digit morphogenesis-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GNA12RHOA10688012515866 Reconstituted Complex
GNA12RHOA10903012515866 Reconstituted Complex
GNA12CDH110903011136230 Reconstituted Complex
GNA12CDH110743411136230 Reconstituted Complex
GNA12CDH210743511136230 Reconstituted Complex
GNA12CDH210903011136230 Reconstituted Complex
GNA12CDH1510744811136230 Reconstituted Complex
GNA12CDH1510903011136230 Reconstituted Complex
GNA12DRD510903012623966 Affinity Capture-Western
GNA12DRD510815012623966 Affinity Capture-Western
GNA12F2R1090308290554 Affinity Capture-Western
GNA12F2R1084488290554 Affinity Capture-Western
TBXA2RGNA121127778290554 Affinity Capture-Western
TBXA2RGNA121090308290554 Affinity Capture-Western
PRKCBGNA121090308824244 Biochemical Activity
PRKCBGNA121115658824244 Biochemical Activity
PRKCDGNA121115668824244 Biochemical Activity
PRKCDGNA121090308824244 Biochemical Activity
PRKCEGNA121115678824244 Biochemical Activity
PRKCEGNA121090308824244 Biochemical Activity
ARHGEF11GNA1210903010026210 Affinity Capture-Western
ARHGEF11GNA1211516410026210 Affinity Capture-Western
ARHGEF12GNA1211694511094164 12515866 Affinity Capture-Western; Phenotypic Enhancement
ARHGEF12GNA1210903011094164 12515866 Affinity Capture-Western; Phenotypic Enhancement
HSP90AA1GNA1210903011598136 Affinity Capture-Western; Two-hybrid
HSP90AA1GNA1210955211598136 Affinity Capture-Western; Two-hybrid
PPP5CGNA1211152812176367 Affinity Capture-Western; Reconstituted Complex
PPP5CGNA1210903012176367 Affinity Capture-Western; Reconstituted Complex
TECGNA1210903012515866 Affinity Capture-Western; Phenotypic Enhancement
TECGNA1211286512515866 Affinity Capture-Western; Phenotypic Enhancement
S1PR4GNA1211424312761884 Reconstituted Complex
S1PR4GNA1210903012761884 Reconstituted Complex
ARHGEF1GNA1211458514634662 Affinity Capture-Western; Reconstituted Complex
ARHGEF1GNA1210903014634662 Affinity Capture-Western; Reconstituted Complex
AKAP13GNA1211638314636890 Affinity Capture-Western
AKAP13GNA1210903014636890 Affinity Capture-Western
MAP3K5GNA1210903017595347 Affinity Capture-Western
MAP3K5GNA1211038117595347 Affinity Capture-Western
RGNEFGNA1212212717595347 Affinity Capture-Western
RGNEFGNA1210903017595347 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:95767
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-050221-1'