Annotation Details for GNA15

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Basic Information Top

Gene Symbol:	GNA15 ( GNA16 )
Gene Full Name:	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
Band:	19p13.3
Quick Links	Entrez ID:2769; OMIM: 139314; Uniprot ID:GNA15_HUMAN; ENSEMBL ID: ENSG00000060558; HGNC ID: 4383
Relate to Another Database:	SFARIGene; denovo-db

Pathways, Diseases and Drugs

AlzGene, PDGene and SZGene

Gene Ontology

Cellular Component:3 results
Molecular Function:7 results
Biological Process:6 results

GO ID	Evidence	Qualifier	GO_term	References
GO:0005834	IBA	-	heterotrimeric G-protein complex	-
GO:0005834	NAS	-	heterotrimeric G-protein complex	10571060
GO:0005886	TAS	-	plasma membrane	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0001664	IBA	-	G-protein coupled receptor binding	-
GO:0003924	IBA	-	GTPase activity	-
GO:0003924	TAS	-	GTPase activity	-
GO:0004871	IGI	-	signal transducer activity	10571060
GO:0005525	IEA	-	GTP binding	-
GO:0031683	IBA	-	G-protein beta/gamma-subunit complex binding	-
GO:0046872	IEA	-	metal ion binding	-

GO ID	Evidence	Qualifier	GO_term	References
GO:0007188	IBA	-	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	-
GO:0007202	TAS	-	activation of phospholipase C activity	7797501
GO:0007204	IGI	-	positive regulation of cytosolic calcium ion concentration	10571060
GO:0007207	TAS	-	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway	7797501
GO:0030168	TAS	-	platelet activation	-
GO:0060158	IBA	-	phospholipase C-activating dopamine receptor signaling pathway	-

Protein-Protein Interaction

BioGRID:6 results
BIND:0 results
HPRD:0 results

Gene Symbol	Interactant	Interaction ID	References	Description
GNA15	ADRBK1	109031	12885252	Affinity Capture-Western; Reconstituted Complex
GNA15	ADRBK1	106665	12885252	Affinity Capture-Western; Reconstituted Complex
TTC1	GNA15	109031	12748287	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
TTC1	GNA15	113116	12748287	Affinity Capture-Western; Reconstituted Complex; Two-hybrid
RGS2	GNA15	109031	12885252	Reconstituted Complex
RGS2	GNA15	111929	12885252	Reconstituted Complex

AlzGene, PDGene and SZGene

Animal Model

Mouse:1 results
Fruit Fly:0 results

MGI ID: MGI:95770
Data Attributes: MGI curated and HomoloGene calculated

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

Studies: 1,036
Genes: 1,379
CNVs/SVs: 5,420
SNVs/Indels: 11,669
de novo Mutations: 5,669
Mosaics: 789
Linkage Regions: 172

Paper Collected: 6/30/2018

Last Update: 8/26/2018

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