AutismKB 2.0

Annotation Details for GNAZ


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Basic Information Top
Gene Symbol:GNAZ ( - )
Gene Full Name: guanine nucleotide binding protein (G protein), alpha z polypeptide
Band: 22q11.22-q11.23
Quick LinksEntrez ID:2781; OMIM: 139160; Uniprot ID:GNAZ_HUMAN; ENSEMBL ID: ENSG00000128266; HGNC ID: 4395
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005635TAS-nuclear envelope2117645
GO:0005783TAS-endoplasmic reticulum2117645
GO:0005829IEA-cytosol-
GO:0005834IBA-heterotrimeric G-protein complex-
GO:0005886TAS-plasma membrane-
GO:0030425IEA-dendrite-
GO:0044297IEA-cell body-
GO:0070062IDA-extracellular exosome23376485
GO ID Evidence Qualifier GO_term References
GO:0001664IBA-G-protein coupled receptor binding-
GO:0003924IBA-GTPase activity-
GO:0003924TAS-GTPase activity-
GO:0005057TAS-signal transducer activity, downstream of receptor2456569
GO:0005525TAS-GTP binding-
GO:0031683IBA-G-protein beta/gamma-subunit complex binding-
GO:0031821IEA-G-protein coupled serotonin receptor binding-
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0006457TAS-protein folding-
GO:0007186TAS-G-protein coupled receptor signaling pathway3129724
GO:0007188IBA-adenylate cyclase-modulating G-protein coupled receptor signaling pathway-
GO:0007193IEA-adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
GNAZEYA210904310906137 Reconstituted Complex; Two-hybrid
GNAZEYA210844010906137 Reconstituted Complex; Two-hybrid
RGS10GNAZ1090438774883 Affinity Capture-Western
RGS10GNAZ1119338774883 Affinity Capture-Western
RGS19GNAZ1090438986788 10906137 Two-hybrid
RGS19GNAZ1155768986788 10906137 Two-hybrid
RGS20GNAZ1090439748279 12414994 Biochemical Activity; Co-localization
RGS20GNAZ1141619748279 12414994 Biochemical Activity; Co-localization
RGS7GNAZ10904310092682 Affinity Capture-Western
RGS7GNAZ11193210092682 Affinity Capture-Western
RAP1GAPGNAZ10904310593970 Reconstituted Complex
RAP1GAPGNAZ11184410593970 Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GNAZrs1805058 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95780
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-090420-3'