AutismKB 2.0

Annotation Details for GNRH1


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Basic Information Top
Gene Symbol:GNRH1 ( GNRH,GRH,LHRH,LNRH )
Gene Full Name: gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
Band: 8p21.2
Quick LinksEntrez ID:2796; OMIM: 152760; Uniprot ID:GON1_HUMAN; ENSEMBL ID: ENSG00000147437; HGNC ID: 4419
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IEA-extracellular space-
GO:0005739IEA-mitochondrion-
GO:0005798IEA-Golgi-associated vesicle-
GO:0030425IEA-dendrite-
GO:0043204IEA-perikaryon-
GO:0043679IEA-axon terminus-
GO:0098556IEA-cytoplasmic side of rough endoplasmic reticulum membrane-
GO:1990008IEA-neurosecretory vesicle-
GO ID Evidence Qualifier GO_term References
GO:0005179TAS-hormone activity2863757
GO:0005183IEA-gonadotropin hormone-releasing hormone activity-
GO ID Evidence Qualifier GO_term References
GO:0007165TAS-signal transduction8692981
GO:0007267TAS-cell-cell signaling1310542
GO:0007275TAS-multicellular organism development2867548
GO:0007565IEA-female pregnancy-
GO:0007568IEA-aging-
GO:0008285TAS-negative regulation of cell proliferation10832105
GO:0010468IEA-regulation of gene expression-
GO:0030238IEA-male sex determination-
GO:0031960IEA-response to corticosteroid-
GO:0032496IEA-response to lipopolysaccharide-
GO:0033087IEA-negative regulation of immature T cell proliferation-
GO:0033574IEA-response to testosterone-
GO:0034695IEA-response to prostaglandin E-
GO:0035864IEA-response to potassium ion-
GO:0043066IEA-negative regulation of apoptotic process-
GO:0044849IEA-estrous cycle-
GO:0045471IEA-response to ethanol-
GO:1990637IEA-response to prolactin-
GO:2000354IEA-regulation of ovarian follicle development-
GO:2001223IEA-negative regulation of neuron migration-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
MEP1AGNRH110905811278902 Biochemical Activity
MEP1AGNRH111038711278902 Biochemical Activity
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GNRH1rs1567126, rs2321049, rs6185 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95789
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018