AutismKB 2.0

Annotation Details for GOT2


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Basic Information Top
Gene Symbol:GOT2 ( FLJ40994,KAT4,KATIV,mitAAT )
Gene Full Name: glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)
Band: 16q21
Quick LinksEntrez ID:2806; OMIM: 138150; Uniprot ID:AATM_HUMAN; ENSEMBL ID: ENSG00000125166; HGNC ID: 4433
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005739IDA-mitochondrion9537447
GO:0005739ISS-mitochondrion-
GO:0005743IEA-mitochondrial inner membrane-
GO:0005759TAS-mitochondrial matrix-
GO:0005886IDA-plasma membrane9537447
GO:0009986IEA-cell surface-
GO:0043204IEA-perikaryon-
GO:0043209IEA-myelin sheath-
GO:0043234IEA-protein complex-
GO:0070062IDA-extracellular exosome20458337
GO ID Evidence Qualifier GO_term References
GO:0003723IDA-RNA binding22681889
GO:0004069EXP-L-aspartate:2-oxoglutarate aminotransferase activity4052435
GO:0004069IDA-L-aspartate:2-oxoglutarate aminotransferase activity2182221
GO:0004069ISS-L-aspartate:2-oxoglutarate aminotransferase activity-
GO:0005543IEA-phospholipid binding-
GO:0016212IEA-kynurenine-oxoglutarate transaminase activity-
GO:0016597IEA-amino acid binding-
GO:0019899IEA-enzyme binding-
GO:0030170IEA-pyridoxal phosphate binding-
GO:0042803IEA-protein homodimerization activity-
GO:0047578TAS-4-hydroxyglutamate transaminase activity-
GO:0080130IEA-L-phenylalanine:2-oxoglutarate aminotransferase activity-
GO ID Evidence Qualifier GO_term References
GO:0006094TAS-gluconeogenesis-
GO:0006103ISS-2-oxoglutarate metabolic process-
GO:0006107IEA-oxaloacetate metabolic process-
GO:0006531ISS-aspartate metabolic process-
GO:0006532IEA-aspartate biosynthetic process-
GO:0006533IDA-aspartate catabolic process2567216
GO:0006536ISS-glutamate metabolic process-
GO:0008652TAS-cellular amino acid biosynthetic process-
GO:0015908IEP-fatty acid transport9537447
GO:0019470TAS-4-hydroxyproline catabolic process21998747
GO:0019550IEA-glutamate catabolic process to aspartate-
GO:0019551IEA-glutamate catabolic process to 2-oxoglutarate-
GO:0045471IDA-response to ethanol9537447
GO:0046487TAS-glyoxylate metabolic process-
GO:0097052IEA-L-kynurenine metabolic process-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
HSPA8GOT21090687559589 Reconstituted Complex
HSPA8GOT21095447559589 Reconstituted Complex
PSMD4GOT210906812601813 Affinity Capture-MS
PSMD4GOT211168312601813 Affinity Capture-MS
THOC7GOT210906816169070 Two-hybrid
THOC7GOT212313816169070 Two-hybrid
MPGGOT210906817353931 Affinity Capture-MS
MPGGOT211049017353931 Affinity Capture-MS
CTNNBIP1GOT212131317353931 Affinity Capture-MS
CTNNBIP1GOT210906817353931 Affinity Capture-MS
No data
No data
AlzGene, PDGene and SZGene Top
No data
No data
Gene Symbol Poly Names Gene overview in SZGene
GOT2rs257620, rs257630, rs30838, rs30842, rs6993, rs7204324 Gene overview in SZGene
Animal Model Top
  • MGI ID: MGI:95792
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-030131-7917'