AutismKB 2.0

Annotation Details for SFN


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:SFN ( YWHAS )
Gene Full Name: stratifin
Band: 1p36.11
Quick LinksEntrez ID:2810; OMIM: 601290; Uniprot ID:1433S_HUMAN; ENSEMBL ID: ENSG00000175793; HGNC ID: 10773
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005615TAS-extracellular space8515476
GO:0005634IEA-nucleus-
GO:0005739IEA-mitochondrion-
GO:0005829IDA-cytosol-
GO:0005829TAS-cytosol-
GO:0030659TAS-cytoplasmic vesicle membrane-
GO:0070062IDA-extracellular exosome19056867
GO ID Evidence Qualifier GO_term References
GO:0005515IPI-protein binding11574543
GO:0008426TAS-protein kinase C inhibitor activity8515476
GO:0019901IEA-protein kinase binding-
GO:0019904IEA-protein domain specific binding-
GO:0042802IPI-identical protein binding15778465
GO:0045296IDA-cadherin binding25468996
GO:0051219IEA-phosphoprotein binding-
GO ID Evidence Qualifier GO_term References
GO:0000079IEA-regulation of cyclin-dependent protein serine/threonine kinase activity-
GO:0001836IDA-release of cytochrome c from mitochondria11574543
GO:0003334IEA-keratinocyte development-
GO:0006469TAS-negative regulation of protein kinase activity8515476
GO:0006977TAS-DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest-
GO:0007165TAS-signal transduction8515476
GO:0008630IDA-intrinsic apoptotic signaling pathway in response to DNA damage11574543
GO:0010482ISS-regulation of epidermal cell division-
GO:0010839IEA-negative regulation of keratinocyte proliferation-
GO:0030307IEA-positive regulation of cell growth-
GO:0031424IEA-keratinization-
GO:0043154IDA-negative regulation of cysteine-type endopeptidase activity involved in apoptotic process11574543
GO:0045606ISS-positive regulation of epidermal cell differentiation-
GO:0046827IEA-positive regulation of protein export from nucleus-
GO:0061024TAS-membrane organization-
GO:0061436ISS-establishment of skin barrier-
GO:0071901IEA-negative regulation of protein serine/threonine kinase activity-
GO:1900740TAS-positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
SFNAPC10682115778465 Affinity Capture-MS
SFNAPC10907215778465 Affinity Capture-MS
SFNAPLP210683115778465 Affinity Capture-MS
SFNAPLP210907215778465 Affinity Capture-MS
SFNARAF10907215778465 Affinity Capture-MS
SFNARAF10686415778465 Affinity Capture-MS
SFNRND310688315778465 Affinity Capture-MS
SFNRND310907215778465 Affinity Capture-MS
SFNBAD10907216189514 Two-hybrid
SFNBAD10704816189514 Two-hybrid
SFNBRAF10907215778465 Affinity Capture-MS
SFNBRAF10714115778465 Affinity Capture-MS
SFNCDK110907210524633 Affinity Capture-Western
SFNCDK110742010524633 Affinity Capture-Western
SFNCHEK110907211896572 Affinity Capture-Western
SFNCHEK110753611896572 Affinity Capture-Western
SFNCSNK2A110907215778465 Affinity Capture-MS
SFNCSNK2A110784115778465 Affinity Capture-MS
SFNDYRK1A10907215778465 Affinity Capture-MS
SFNDYRK1A10819215778465 Affinity Capture-MS
SFNMARK210907215778465 Affinity Capture-MS
SFNMARK210832615778465 Affinity Capture-MS
TP53SFN10907211896572 14517281 17546054 Affinity Capture-Western; Reconstituted Complex
TP53SFN11301011896572 14517281 17546054 Affinity Capture-Western; Reconstituted Complex
TRIM25SFN11350012075357 Affinity Capture-Western
TRIM25SFN10907212075357 Affinity Capture-Western
NR3C1SFN10907212730237 Two-hybrid
NR3C1SFN10916512730237 Two-hybrid
HDAC9SFN10907215166223 Affinity Capture-Western
HDAC9SFN11508315166223 Affinity Capture-Western
SH2D3ASFN10907215778465 Affinity Capture-MS
SH2D3ASFN11535615778465 Affinity Capture-MS
DCAF7SFN11553215778465 Affinity Capture-MS
DCAF7SFN10907215778465 Affinity Capture-MS
PAK4SFN10907215778465 Affinity Capture-MS
PAK4SFN11558615778465 Affinity Capture-MS
MAP3K2SFN11596915778465 Affinity Capture-MS
MAP3K2SFN10907215778465 Affinity Capture-MS
SRSF10SFN10907215778465 Affinity Capture-MS
SRSF10SFN11599015778465 Affinity Capture-MS
PKP3SFN11635715778465 Affinity Capture-MS
PKP3SFN10907215778465 Affinity Capture-MS
DTX2SFN10907215778465 Affinity Capture-MS
DTX2SFN12526615778465 Affinity Capture-MS
PARD3BSFN10907215778465 Affinity Capture-MS
PARD3BSFN12559215778465 Affinity Capture-MS
TRIM32SFN10907215778465 Affinity Capture-MS
TRIM32SFN11660815778465 Affinity Capture-MS
MYCBP2SFN10907215778465 Affinity Capture-MS
MYCBP2SFN11670915778465 Affinity Capture-MS
SIPA1L3SFN11672215778465 Affinity Capture-MS
SIPA1L3SFN10907215778465 Affinity Capture-MS
MPRIPSFN10907215778465 Affinity Capture-MS
MPRIPSFN11677615778465 Affinity Capture-MS
ANKS1ASFN10907215778465 Affinity Capture-MS
ANKS1ASFN11688915778465 Affinity Capture-MS
NEDD4LSFN10907215778465 Affinity Capture-MS
NEDD4LSFN11691515778465 Affinity Capture-MS
SASH1SFN10907215778465 Affinity Capture-MS
SASH1SFN11691615778465 Affinity Capture-MS
ISCUSFN10907215778465 Affinity Capture-MS
ISCUSFN11703815778465 Affinity Capture-MS
SRRM2SFN10907215778465 Affinity Capture-MS
SRRM2SFN11707115778465 Affinity Capture-MS
KLHDC2SFN10907215778465 Affinity Capture-MS
KLHDC2SFN11712315778465 Affinity Capture-MS
SH3BP4SFN10907215778465 Affinity Capture-MS
SH3BP4SFN11719415778465 Affinity Capture-MS
OSBPL3SFN10907215778465 Affinity Capture-MS
OSBPL3SFN11749715778465 Affinity Capture-MS
SIPA1L1SFN10907215778465 Affinity Capture-MS
SIPA1L1SFN11750315778465 Affinity Capture-MS
ARHGEF16SFN10907215778465 Affinity Capture-MS
ARHGEF16SFN11808515778465 Affinity Capture-MS
ZNF638SFN10907215778465 Affinity Capture-MS
ZNF638SFN11814515778465 Affinity Capture-MS
GRB7SFN10907215778465 Affinity Capture-MS
GRB7SFN10914315778465 Affinity Capture-MS
RACGAP1SFN10907215778465 Affinity Capture-MS
RACGAP1SFN11889215778465 Affinity Capture-MS
HNRNPUSFN10907215778465 Affinity Capture-MS
HNRNPUSFN10943315778465 Affinity Capture-MS
IRS1SFN10907215778465 Affinity Capture-MS
IRS1SFN10987415778465 Affinity Capture-MS
KIF5BSFN10907215778465 Affinity Capture-MS
KIF5BSFN11000015778465 Affinity Capture-MS
KLC1SFN10907215778465 Affinity Capture-MS
KLC1SFN11002915778465 Affinity Capture-MS
LAD1SFN10907215778465 Affinity Capture-MS
LAD1SFN11009515778465 Affinity Capture-MS
ABLIM1SFN10907215778465 Affinity Capture-MS
ABLIM1SFN11017115778465 Affinity Capture-MS
LMO7SFN11019315778465 Affinity Capture-MS
LMO7SFN10907215778465 Affinity Capture-MS
MARK1SFN11030915778465 Affinity Capture-MS
MARK1SFN10907215778465 Affinity Capture-MS
HDAC7SFN10907215778465 Affinity Capture-MS
HDAC7SFN11961315778465 Affinity Capture-MS
LSRSFN10907215778465 Affinity Capture-MS
LSRSFN11962915778465 Affinity Capture-MS
ZAKSFN10907215778465 Affinity Capture-MS
ZAKSFN11972515778465 Affinity Capture-MS
PIK3C2BSFN10907215778465 Affinity Capture-MS
PIK3C2BSFN11130515778465 Affinity Capture-MS
PI4KBSFN10907215778465 Affinity Capture-MS
PI4KBSFN11131615778465 Affinity Capture-MS
PKP2SFN10907215778465 Affinity Capture-MS
PKP2SFN11133515778465 Affinity Capture-MS
PTOV1SFN10907215778465 Affinity Capture-MS
PTOV1SFN11979215778465 Affinity Capture-MS
PPP1R3DSFN11150115778465 Affinity Capture-MS
PPP1R3DSFN10907215778465 Affinity Capture-MS
RALGPS2SFN10907215778465 Affinity Capture-MS
RALGPS2SFN12041315778465 Affinity Capture-MS
PARD3SFN10907215778465 Affinity Capture-MS
PARD3SFN12113415778465 Affinity Capture-MS
SPIRE1SFN10907215778465 Affinity Capture-MS
SPIRE1SFN12123715778465 Affinity Capture-MS
CGNSFN10907215778465 Affinity Capture-MS
CGNSFN12158915778465 Affinity Capture-MS
ARHGAP21SFN10907215778465 Affinity Capture-MS
ARHGAP21SFN12163615778465 Affinity Capture-MS
SHROOM3SFN10907215778465 Affinity Capture-MS
SHROOM3SFN12166515778465 Affinity Capture-MS
PTPN2SFN10907215778465 Affinity Capture-MS
PTPN2SFN11173715778465 Affinity Capture-MS
PTPN3SFN10907215778465 Affinity Capture-MS
PTPN3SFN11174015778465 Affinity Capture-MS
RAF1SFN11183115778465 Affinity Capture-MS
RAF1SFN10907215778465 Affinity Capture-MS
SAV1SFN10907215778465 Affinity Capture-MS
SAV1SFN12191715778465 Affinity Capture-MS
KLC2SFN10907215778465 Affinity Capture-MS
KLC2SFN12231315778465 Affinity Capture-MS
ST5SFN10907215778465 Affinity Capture-MS
ST5SFN11264215778465 Affinity Capture-MS
WEE1SFN11330315778465 Affinity Capture-MS
WEE1SFN10907215778465 Affinity Capture-MS
YWHAGSFN11336415778465 Affinity Capture-MS
YWHAGSFN10907215778465 Affinity Capture-MS
MAPKAP1SFN10907215778465 Affinity Capture-MS
MAPKAP1SFN12255115778465 Affinity Capture-MS
SHCBP1SFN10907215778465 Affinity Capture-MS
SHCBP1SFN12289815778465 Affinity Capture-MS
ARHGEF5SFN10907215778465 Affinity Capture-MS
ARHGEF5SFN11369615778465 Affinity Capture-MS
GANSFN11380015778465 Affinity Capture-MS
GANSFN10907215778465 Affinity Capture-MS
ITCHSFN10907215778465 Affinity Capture-MS
ITCHSFN12374715778465 Affinity Capture-MS
SORBS2SFN10907215778465 Affinity Capture-MS
SORBS2SFN11404715778465 Affinity Capture-MS
RAE1SFN10907215778465 Affinity Capture-MS
RAE1SFN11405415778465 Affinity Capture-MS
PPFIBP2SFN11406715778465 Affinity Capture-MS
PPFIBP2SFN10907215778465 Affinity Capture-MS
TNS4SFN10907215778465 Affinity Capture-MS
TNS4SFN12438315778465 Affinity Capture-MS
PPFIBP1SFN11406815778465 Affinity Capture-MS
PPFIBP1SFN10907215778465 Affinity Capture-MS
RHPN2SFN10907215778465 Affinity Capture-MS
RHPN2SFN12452115778465 Affinity Capture-MS
IRS2SFN11420915778465 Affinity Capture-MS
IRS2SFN10907215778465 Affinity Capture-MS
TNK1SFN11425315778465 Affinity Capture-MS
TNK1SFN10907215778465 Affinity Capture-MS
SYNJ2SFN11439115778465 Affinity Capture-MS
SYNJ2SFN10907215778465 Affinity Capture-MS
USP8SFN11455515778465 Affinity Capture-MS
USP8SFN10907215778465 Affinity Capture-MS
MAGI1SFN11465515778465 Affinity Capture-MS
MAGI1SFN10907215778465 Affinity Capture-MS
CYTH2SFN11468715778465 Affinity Capture-MS
CYTH2SFN10907215778465 Affinity Capture-MS
TJP2SFN11480915778465 Affinity Capture-MS
TJP2SFN10907215778465 Affinity Capture-MS
KIF23SFN11487315778465 Affinity Capture-MS
KIF23SFN10907215778465 Affinity Capture-MS
BCAR1SFN11493415778465 Affinity Capture-MS
BCAR1SFN10907215778465 Affinity Capture-MS
ARHGAP32SFN11509115778465 Affinity Capture-MS
ARHGAP32SFN10907215778465 Affinity Capture-MS
HDAC4SFN11510615778465 Affinity Capture-MS
HDAC4SFN10907215778465 Affinity Capture-MS
ARHGAP11ASFN10907215778465 Affinity Capture-MS
ARHGAP11ASFN11516215778465 Affinity Capture-MS
ARHGEF17SFN11516615778465 Affinity Capture-MS
ARHGEF17SFN10907215778465 Affinity Capture-MS
ERRFI1SFN10907215778465 Affinity Capture-MS; Affinity Capture-Western
ERRFI1SFN11992315778465 Affinity Capture-MS; Affinity Capture-Western
JUBSFN10907215778465 Affinity Capture-MS; Affinity Capture-Western
JUBSFN12439315778465 Affinity Capture-MS; Affinity Capture-Western
MARK3SFN11031015778465 16189514 Affinity Capture-MS; Two-hybrid
MARK3SFN10907215778465 16189514 Affinity Capture-MS; Two-hybrid
PLK4SFN11595616189514 Affinity Capture-Western; Two-hybrid
PLK4SFN10907216189514 Affinity Capture-Western; Two-hybrid
TBL3SFN11585316189514 Two-hybrid
TBL3SFN10907216189514 Two-hybrid
WDYHV1SFN10907216189514 Two-hybrid
WDYHV1SFN12040516189514 Two-hybrid
PLEKHF2SFN10907216189514 Two-hybrid
PLEKHF2SFN12279116189514 Two-hybrid
CHST1SFN11410416189514 Two-hybrid
CHST1SFN10907216189514 Two-hybrid
FAM189A2SFN11480816189514 Two-hybrid
FAM189A2SFN10907216189514 Two-hybrid
GPRIN2SFN11507016189514 Two-hybrid
GPRIN2SFN10907216189514 Two-hybrid
KIAA0408SFN10907216189514 Two-hybrid
KIAA0408SFN11507816189514 Two-hybrid
MDM4SFN10907216511560 Affinity Capture-Western
MDM4SFN11035916511560 Affinity Capture-Western
ING1SFN10907216581770 Reconstituted Complex
ING1SFN10983316581770 Reconstituted Complex
MDM2SFN11035817546054 Affinity Capture-Western; Reconstituted Complex
MDM2SFN10907217546054 Affinity Capture-Western; Reconstituted Complex
UBCSFN10907218382127 Affinity Capture-Western
UBCSFN11316418382127 Affinity Capture-Western
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1891831
  • Data Attributes: MGI curated and HomoloGene calculated
No data
No data

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved