AutismKB 2.0

Annotation Details for ANGPT2


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Basic Information Top
Gene Symbol:ANGPT2 ( AGPT2,ANG2 )
Gene Full Name: angiopoietin 2
Band: 8p23.1
Quick LinksEntrez ID:285; OMIM: 601922; Uniprot ID:ANGP2_HUMAN; ENSEMBL ID: ENSG00000091879; HGNC ID: 485
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005576TAS-extracellular region-
GO:0005615IDA-extracellular space9660821
GO:0005634IEA-nucleus-
GO:0005886IEA-plasma membrane-
GO:0042995IEA-cell projection-
GO ID Evidence Qualifier GO_term References
GO:0005102TAS-receptor binding9204896
GO:0005515IPI-protein binding20708158
GO:0030971IPI-receptor tyrosine kinase binding19922791
GO:0046872IEA-metal ion binding-
GO ID Evidence Qualifier GO_term References
GO:0001525IEA-angiogenesis-
GO:0001666IEA-response to hypoxia-
GO:0007165TAS-signal transduction10766762
GO:0007281IEA-germ cell development-
GO:0009314IEA-response to radiation-
GO:0009612IEA-response to mechanical stimulus-
GO:0009749IEA-response to glucose-
GO:0010812IEA-negative regulation of cell-substrate adhesion-
GO:0014070IEA-response to organic cyclic compound-
GO:0014823IEA-response to activity-
GO:0016525IEA-negative regulation of angiogenesis-
GO:0031100IEA-animal organ regeneration-
GO:0043537IDA-negative regulation of blood vessel endothelial cell migration9660821
GO:0045766IEA-positive regulation of angiogenesis-
GO:0048014IDA-Tie signaling pathway19922791
GO:0050900TAS-leukocyte migration-
GO:0050928IDA-negative regulation of positive chemotaxis9660821
GO:0060135IEA-maternal process involved in female pregnancy-
GO:0071363IEA-cellular response to growth factor stimulus-
GO:0072012ISS-glomerulus vasculature development-
Protein-Protein Interaction Top
Gene Symbol Interactant Interaction ID References Description
TEKANGPT21128699204896 9723709 12427764 Affinity Capture-Western; Reconstituted Complex
TEKANGPT21067829204896 9723709 12427764 Affinity Capture-Western; Reconstituted Complex
No data
No data
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1202890
  • Data Attributes: MGI curated and HomoloGene calculated
SELECT * FROM lijr_20110218_zfin_genotype_phenotype WHERE ZFIN_Gene_ID='ZDB-GENE-010817-2'