AutismKB 2.0

Annotation Details for GPR35


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Basic Information Top
Gene Symbol:GPR35 ( - )
Gene Full Name: G protein-coupled receptor 35
Band: 2q37.3
Quick LinksEntrez ID:2859; OMIM: 602646; Uniprot ID:GPR35_HUMAN; ENSEMBL ID: ENSG00000178623; HGNC ID: 4492
Relate to Another Database: SFARIGene; denovo-db
Gene Ontology Top
GO ID Evidence Qualifier GO_term References
GO:0005886TAS-plasma membrane-
GO:0005887IDA-integral component of plasma membrane16754668
GO ID Evidence Qualifier GO_term References
GO:0004930IDA-G-protein coupled receptor activity16754668
GO:0016494IMP-C-X-C chemokine receptor activity25411203
GO ID Evidence Qualifier GO_term References
GO:0007010IEA-cytoskeleton organization-
GO:0007186IDA-G-protein coupled receptor signaling pathway16754668
GO:0007204IMP-positive regulation of cytosolic calcium ion concentration25411203
GO:0035025IBA-positive regulation of Rho protein signal transduction-
GO:0051482IBA-positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway-
GO:0070098IDA-chemokine-mediated signaling pathway25411203
GO:0070098IMP-chemokine-mediated signaling pathway25411203
GO:1901386IMP-negative regulation of voltage-gated calcium channel activity17940199
GO:1904456IEA-negative regulation of neuronal action potential-
Protein-Protein Interaction Top
AlzGene, PDGene and SZGene Top
Animal Model Top
  • MGI ID: MGI:1929509
  • Data Attributes: MGI curated and HomoloGene calculated
No data
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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